RTW INVESTMENTS, LP Q3 2016 Filing

Filed November 14, 2016

Portfolio Value

$330.9B

Holdings

36

Report Date

Q3 2016

Filing Type

13F-HR

All Holdings (36 positions)

#StockSharesValue% PortfolioType
1
MDRXAlnylam Pharmaceuticals Inc
948,286$64.3B19.43%
2
Avexis Inc
825,980$34.0B10.29%
3
AGENEURAgenus Inc
4,141,644$29.7B8.99%
4
La Jolla Pharmaceutical Co
1,170,151$27.8B8.41%
5
BCRXBioCryst Pharmaceuticals Inc
4,204,579$18.5B5.60%
6
INCYIncyte Corp
191,151$18.0B5.45%
7
Achillion Pharmaceuticals Inc
2,208,749$17.9B5.41%
8
Dicerna Pharmaceuticals Inc
2,026,894$11.9B3.60%
9
BMYBristol-Myers Squibb Co
209,701$11.3B3.42%
10
GQ9SPDR Gold Shares ETF
83,000$10.4B3.15%
11
ATRAGBXAtara Biotherapeutics Inc.
458,113$9.8B2.96%
12
ARWRArrowhead Pharmaceuticals Inc
1,116,777$8.2B2.48%
13
HRTXHeron Therapeutics Inc
386,787$6.7B2.01%
14
Viveve Medical Inc
839,274$6.1B1.83%
15
bluebird bio Inc
87,734$5.9B1.80%
16
Corium International Inc
1,045,747$5.9B1.78%
17
Invuity Inc
392,838$5.4B1.63%
18
Celldex Therapeutics Inc
1,243,164$5.0B1.52%
19
Medicines Co
123,000$4.6B1.40%
20
OMEROmeros Corp
383,012$4.3B1.29%
21
TCMDTactile Systems Technology Inc Cmn
227,599$4.3B1.29%
22
Barclays Bank iPath Dow Jones-UBS Coffee Subindex TR ETN
180,500$4.0B1.21%
23
RGNXRegenxbio Inc
238,740$3.3B1.01%
24
Oxford Immunotec Global PLC
235,900$3.0B0.90%
25
Five Prime Therapeutics Inc
44,044$2.3B0.70%
26
GBTUSDGlobal Blood Therapeutics Inc
95,714$2.2B0.67%
27
3M4Masimo Corp
25,900$1.5B0.47%
28
NVAXNOVAVAX INC
4,787$996.0M0.30%Call
29
MRTXEURMirati Therapeutics Inc
129,129$854.0M0.26%
30
SRTSSensus Healthcare Inc Cmn
125,700$773.0M0.23%
31
Biopharmx Corp
700,636$389.0M0.12%
32
Audentes Therapeutics Inc
20,000$356.0M0.11%
33
NTRANatera Inc
31,693$352.0M0.11%
34
MANNKIND CORP
4,385$272.0M0.08%Put
35
Nivalis Therapeutics Inc
30,000$244.0M0.07%
36
Abeona Therapeutics Inc
19,391$116.0M0.04%