TWO SIGMA ADVISERS, LP Q4 2021 Filing
Filed February 14, 2022
Portfolio Value
$39.9B
Holdings
2,591
Report Date
Q4 2021
Filing Type
13F-HR
All Holdings (2,591 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | MSFTMICROSOFT CORP | 2,763,900 | $929.6B | 2328.12% | |
| 2 | JNJJOHNSON & JOHNSON | 3,186,900 | $545.2B | 1365.44% | |
| 3 | VVISA INC | 2,471,400 | $535.6B | 1341.38% | |
| 4 | AAPLAPPLE INC | 2,933,300 | $520.9B | 1304.54% | |
| 5 | LLYLILLY ELI & CO | 1,776,000 | $490.6B | 1228.65% | |
| 6 | METAMETA PLATFORMS INC | 1,455,400 | $489.5B | 1226.04% | |
| 7 | KOCOCA COLA CO | 8,038,301 | $475.9B | 1192.04% | |
| 8 | MDTMEDTRONIC PLC | 4,171,620 | $431.6B | 1080.85% | |
| 9 | CHTRCHARTER COMMUNICATIONS INC N | 651,825 | $425.0B | 1064.36% | |
| 10 | BMYBRISTOL-MYERS SQUIBB CO | 6,616,599 | $412.5B | 1033.24% | |
| 11 | SPGIS&P GLOBAL INC | 870,800 | $411.0B | 1029.26% | |
| 12 | AMGNAMGEN INC | 1,808,400 | $406.8B | 1018.94% | |
| 13 | TSLATESLA INC | 383,784 | $405.6B | 1015.78% | |
| 14 | ZSZSCALER INC | 1,211,500 | $389.3B | 975.00% | |
| 15 | PFEPFIZER INC | 6,483,701 | $382.9B | 958.90% | |
| 16 | ATVIEURACTIVISION BLIZZARD INC | 5,610,800 | $373.3B | 934.92% | |
| 17 | NVDANVIDIA CORPORATION | 1,256,400 | $369.5B | 925.48% | |
| 18 | MRKMERCK & CO INC | 4,700,599 | $360.3B | 902.27% | |
| 19 | CATCATERPILLAR INC | 1,737,800 | $359.3B | 899.82% | |
| 20 | TEAMATLASSIAN CORP PLC | 939,500 | $358.2B | 897.19% | |
| 21 | BSXBOSTON SCIENTIFIC CORP | 8,381,260 | $356.0B | 891.71% | |
| 22 | CERNCHFCERNER CORP | 3,758,433 | $349.0B | 874.20% | |
| 23 | DDOGDATADOG INC | 1,932,800 | $344.3B | 862.19% | |
| 24 | PYPLPAYPAL HLDGS INC | 1,716,100 | $323.6B | 810.53% | |
| 25 | ETSYETSY INC | 1,453,100 | $318.1B | 796.80% | |
| 26 | INTCINTEL CORP | 6,114,675 | $314.9B | 788.70% | |
| 27 | MAMASTERCARD INCORPORATED | 875,200 | $314.5B | 787.62% | |
| 28 | FTNTFORTINET INC | 872,444 | $313.6B | 785.32% | |
| 29 | CSXCSX CORP | 8,230,600 | $309.5B | 775.09% | |
| 30 | AMDADVANCED MICRO DEVICES INC | 2,075,657 | $298.7B | 748.08% | |
| 31 | TMOTHERMO FISHER SCIENTIFIC INC | 435,500 | $290.6B | 727.78% | |
| 32 | ABBVABBVIE INC | 2,106,166 | $285.2B | 714.24% | |
| 33 | ORCLORACLE CORP | 3,196,100 | $278.7B | 698.10% | |
| 34 | PANWPALO ALTO NETWORKS INC | 497,302 | $276.9B | 693.45% | |
| 35 | HONHONEYWELL INTL INC | 1,307,400 | $272.6B | 682.76% | |
| 36 | FCXFREEPORT-MCMORAN INC | 6,451,800 | $269.2B | 674.31% | |
| 37 | ILMNILLUMINA INC | 702,400 | $267.2B | 669.27% | |
| 38 | CRWDCROWDSTRIKE HLDGS INC | 1,288,000 | $263.7B | 660.50% | |
| 39 | BAXBAXTER INTL INC | 2,961,550 | $254.2B | 636.70% | |
| 40 | NVSNNOVARTIS AG | 2,869,700 | $251.0B | 628.67% | |
| 41 | TRVCCITIGROUP INC | 4,152,500 | $250.8B | 628.06% | |
| 42 | EMREMERSON ELEC CO | 2,692,100 | $250.3B | 626.85% | |
| 43 | GILDGILEAD SCIENCES INC | 3,443,100 | $250.0B | 626.15% | |
| 44 | GOOGLALPHABET INC | 84,900 | $246.0B | 616.02% | |
| 45 | REGNREGENERON PHARMACEUTICALS | 388,500 | $245.3B | 614.48% | |
| 46 | EWEDWARDS LIFESCIENCES CORP | 1,878,003 | $243.3B | 609.34% | |
| 47 | MDLZMONDELEZ INTL INC | 3,599,899 | $238.7B | 597.86% | |
| 48 | DC4DEXCOM INC | 441,369 | $237.0B | 593.56% | |
| 49 | CMCSACOMCAST CORP NEW | 4,384,600 | $220.7B | 552.70% | |
| 50 | MCHPMICROCHIP TECHNOLOGY INC. | 2,431,000 | $211.6B | 530.07% | |
| 51 | AG8AGILENT TECHNOLOGIES INC | 1,266,800 | $202.2B | 506.53% | |
| 52 | XLVSELECT SECTOR SPDR TR | 1,414,500 | $199.3B | 499.13% | |
| 53 | ABNBAIRBNB INC | 1,178,400 | $196.2B | 491.37% | |
| 54 | AMZNAMAZON COM INC | 58,811 | $196.1B | 491.13% | |
| 55 | NDQINVESCO QQQ TR | 486,580 | $193.6B | 484.85% | |
| 56 | NSCNORFOLK SOUTHN CORP | 638,300 | $190.0B | 475.93% | |
| 57 | TWTRUSDTWITTER INC | 4,363,300 | $188.6B | 472.31% | |
| 58 | ADPAUTOMATIC DATA PROCESSING IN | 760,800 | $187.6B | 469.85% | |
| 59 | AZOAUTOZONE INC | 85,274 | $178.8B | 447.73% | |
| 60 | STXSEAGATE TECHNOLOGY HLDNGS PL | 1,571,400 | $177.5B | 444.65% | |
| 61 | SPYSPDR S&P 500 ETF TR | 373,303 | $177.3B | 444.07% | |
| 62 | DKNG1USDDRAFTKINGS INC | 6,343,100 | $174.2B | 436.41% | |
| 63 | CP.TOCANADIAN PAC RY LTD | 2,407,336 | $173.2B | 433.75% | |
| 64 | ELVANTHEM INC | 368,662 | $170.9B | 428.00% | |
| 65 | VMWEURVMWARE INC | 1,455,042 | $168.6B | 422.29% | |
| 66 | PSTGPURE STORAGE INC | 4,988,400 | $162.4B | 406.67% | |
| 67 | ECLECOLAB INC | 663,246 | $155.6B | 389.69% | |
| 68 | UNPUNION PAC CORP | 615,101 | $155.0B | 388.11% | |
| 69 | USMVISHARES TR | 1,879,800 | $152.1B | 380.88% | |
| 70 | CUCAAVIS BUDGET GROUP | 718,500 | $149.0B | 373.17% | |
| 71 | XLFISELECT SECTOR SPDR TR | 1,932,100 | $149.0B | 373.14% | |
| 72 | MRO*MARATHON OIL CORP | 9,010,000 | $147.9B | 370.53% | |
| 73 | —IHS MARKIT LTD | 1,109,085 | $147.4B | 369.22% | |
| 74 | DTDYNATRACE INC | 2,423,500 | $146.3B | 366.31% | |
| 75 | ANETEURARISTA NETWORKS INC | 937,000 | $134.7B | 337.35% | |
| 76 | XLISELECT SECTOR SPDR TR | 1,256,500 | $132.9B | 332.98% | |
| 77 | DBXDROPBOX INC | 5,304,700 | $130.2B | 326.03% | |
| 78 | XLKSELECT SECTOR SPDR TR | 741,400 | $128.9B | 322.85% | |
| 79 | INTUINTUIT | 197,200 | $126.8B | 317.68% | |
| 80 | XOMEXXON MOBIL CORP | 2,052,900 | $125.6B | 314.61% | |
| 81 | BKNGBOOKING HOLDINGS INC | 51,700 | $124.0B | 310.66% | |
| 82 | DHRDANAHER CORPORATION | 373,000 | $122.7B | 307.36% | |
| 83 | CHKPCHECK POINT SOFTWARE TECH LT | 1,032,200 | $120.3B | 301.33% | |
| 84 | DUKDUKE ENERGY CORP NEW | 1,135,500 | $119.1B | 298.33% | |
| 85 | ZEN1EURZENDESK INC | 1,119,500 | $116.8B | 292.41% | |
| 86 | SNPSSYNOPSYS INC | 311,400 | $114.8B | 287.40% | |
| 87 | VIGVANGUARD SPECIALIZED FUNDS | 641,800 | $110.2B | 276.07% | |
| 88 | BIIBBIOGEN INC | 455,200 | $109.2B | 273.53% | |
| 89 | RSGREPUBLIC SVCS INC | 764,900 | $106.7B | 267.15% | |
| 90 | VEEVVEEVA SYS INC | 413,700 | $105.7B | 264.71% | |
| 91 | ISRGINTUITIVE SURGICAL INC | 293,609 | $105.5B | 264.22% | |
| 92 | NETCLOUDFLARE INC | 800,000 | $105.2B | 263.48% | |
| 93 | ORLYOREILLY AUTOMOTIVE INC | 148,400 | $104.8B | 262.49% | |
| 94 | CNRCANADIAN NATL RY CO | 824,372 | $101.3B | 253.67% | |
| 95 | IQVIQVIA HLDGS INC | 354,600 | $100.0B | 250.57% | |
| 96 | IVVISHARES TR | 206,500 | $98.5B | 246.69% | |
| 97 | STLASTELLANTIS N.V | 5,205,205 | $97.7B | 244.57% | |
| 98 | —MIMECAST LTD | 1,204,700 | $95.9B | 240.08% | |
| 99 | INMDINMODE LTD | 1,340,500 | $94.6B | 236.96% | |
| 100 | ICLRICON PLC | 300,802 | $93.2B | 233.32% |
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