Who Owns Enanta Pharmaceuticals, Inc. (ENTA)?Hedge Fund & Institutional Holders

$13.06-0.34 (-2.57%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$5.800000043718e+291T

% of Float Held

1.846438648068706e+258%

QoQ Change in Holders

+6 / -7

Price History

$4.26$7.41$10.55$13.70$16.85Sep 24Jun 25Mar 26

ENTA — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
JANUS HENDERSON GROUP PLCIncreased+1.8M+$34.7B
FARALLON CAPITAL MANAGEMENT LLCIncreased+650K+$18.3B
Hillsdale Investment Management Inc.New Position+422K+$6.0B
RENAISSANCE TECHNOLOGIES LLCIncreased+163K+$4.3B
Invesco Ltd.Increased+194K+$3.3B
TWO SIGMA INVESTMENTS, LPIncreased+225K+$3.3B
Point72 Asset Management, L.P.Increased+139K+$2.4B
DIADEMA PARTNERS LPNew Position+65K+$1.0B
GOLDMAN SACHS GROUP INCIncreased+52K+$1.0B
CHARLES SCHWAB INVESTMENT MANAGEMENT INCIncreased+52K+$1.0B
PANAGORA ASSET MANAGEMENT INCNew Position+67K+$1.0B
NORTHERN TRUST CORPIncreased+34K+$655.1M
ADAR1 Capital Management, LLCNew Position+41K+$652.0M
Sio Capital Management, LLCNew Position+40K+$630.0M
State of WyomingNew Position+33K+$518.0M

ENTA — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Commodore Capital LPClosed Position-800K-$9.6B
Stonepine Capital Management, LLCDecreased-205K-$2.1B
JACOBS LEVY EQUITY MANAGEMENT, INCClosed Position-169K-$2.0B
Nuveen, LLCDecreased-79K-$2.0B
Trexquant Investment LPClosed Position-127K-$1.5B
TANG CAPITAL MANAGEMENT LLCClosed Position-127K-$1.5B
SUSQUEHANNA INTERNATIONAL GROUP, LLPDecreased-107K-$1.4B
MILLENNIUM MANAGEMENT LLCDecreased-278K-$1.3B
STEMPOINT CAPITAL LPClosed Position-75K-$900.1M
D. E. Shaw & Co., Inc.Decreased-58K-$702.2M
Cubist Systematic Strategies, LLCClosed Position-50K-$598.3M
AMERICAN CENTURY COMPANIES INCDecreased-15K-$581.4M
JPMORGAN CHASE & CODecreased-11K-$481.0M
IEQ CAPITAL, LLCDecreased-1K-$451.1M
Graham Capital Management, L.P.Closed Position-37K-$446.8M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1JANUS HENDERSON GROUP PLC3,729,659$58.0B25.97%Share
2FARALLON CAPITAL MANAGEMENT LLC2,772,262$43.7B206.29%Share
3RENAISSANCE TECHNOLOGIES LLC642,200$10.0B15.51%Share
4MILLENNIUM MANAGEMENT LLC670,428$10.0B4.21%Share
5Hillsdale Investment Management Inc.422,300$6.0B0.17%Share
6Point72 Asset Management, L.P.438,939$6.0B6.71%Share
7TWO SIGMA INVESTMENTS, LP285,448$4.0B5.64%Share
8Invesco Ltd.246,185$3.9B0.60%Share
9DIMENSIONAL FUND ADVISORS LP192,189$3.0B0.63%Share
10AQR CAPITAL MANAGEMENT LLC224,191$3.0B1.57%Share
11GOLDMAN SACHS GROUP INC191,521$3.0B0.37%Share
12CHARLES SCHWAB INVESTMENT MANAGEMENT INC218,636$3.0B0.47%Share
13NORTHERN TRUST CORP221,042$3.0B0.38%Share
14TWO SIGMA ADVISERS, LP143,300$2.0B3.89%Share
15Stonepine Capital Management, LLC100,000$1.6B1.15%Share
16PDT Partners, LLC69,197$1.1B0.07%Share
17DIADEMA PARTNERS LP65,138$1.0B0.18%Share
18SUSQUEHANNA INTERNATIONAL GROUP, LLP99,400$1.0B0.12%Call
19JPMORGAN CHASE & CO93,995$1.0B0.06%Share
20PANAGORA ASSET MANAGEMENT INC66,990$1.0B3.54%Share
21Connor, Clark & Lunn Investment Management Ltd.103,903$1.0B2.62%Share
22SEI INVESTMENTS CO98,779$1.0B0.99%Share
23D. E. Shaw & Co., Inc.98,375$1.0B0.55%Share
24D. E. Shaw & Co., Inc.69,339$1.0B0.55%Share
25Assenagon Asset Management S.A.45,877$723.0M1.00%Share
26ADAR1 Capital Management, LLC41,357$652.0M0.05%Share
27Sio Capital Management, LLC40,000$630.0M0.10%Share
28State of Wyoming32,887$518.0M0.06%Share
29Persistent Asset Partners Ltd17,466$275.0M0.12%Share
30GROUP ONE TRADING LLC14,600$230.0M0.40%Call
31UBS Group AG5,059$79.0M0.01%Share
32Invesco Ltd.3,813$60.0M0.01%Share
33Invesco Ltd.3,813$60.0M0.01%Share
34STRS OHIO3,200$50.0M0.19%Share
35Krensavage Asset Management, LLC2,766,390$43.6M15.41%Share
36VANGUARD GROUP INC2,118,937$33.0M0.48%Share
37Deep Track Capital, LP1,956,867$30.9M0.55%Share
38GAMMA Investing LLC1,331$20.0M0.00%Share
39BlackRock, Inc.1,230,943$19.0M0.32%Share
40ACADIAN ASSET MANAGEMENT LLC885,126$13.0M0.02%Share
41BlackRock, Inc.852,059$13.0M0.22%Share
42BlackRock, Inc.764,012$12.0M0.20%Share
43True Wealth Design, LLC645$10.0M0.00%Share
44GF FUND MANAGEMENT CO. LTD.565$8.0M0.14%Share
45STATE STREET CORP523,715$8.0M0.00%Share
46Spruce Street Capital LP389,687$6.1M2.03%Share
47Red Tortoise LLC364$5.0M0.00%Share
48COMERICA BANK367$5.0M0.02%Share
49NISA INVESTMENT ADVISORS, LLC340$5.0M0.02%Share
50GROUP ONE TRADING LLC300$4.0M0.01%Put

ENTA Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025130$171.6B+30
Q3 2025100$127.0B+13
Q2 202587$41.5B-22
Q1 2025109$69.2B+4
Q4 2024105$57.8B+5
Q3 2024100$4.4T+9
Q2 202491$11.0T-5
Q1 202496$326.5T—

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As of Q4 2025, 50 institutional investors hold ENTA (Enanta Pharmaceuticals, Inc.). The largest holder is JANUS HENDERSON GROUP PLC with $58.0B in shares. This quarter, 6 institutions opened new positions and 7 closed their positions.

Frequently Asked Questions

How many hedge funds own ENTA?

As of Q4 2025, 50 institutional investors report holding ENTA (Enanta Pharmaceuticals, Inc.) in their 13F filings.

Who is the largest institutional holder of ENTA?

The largest institutional holder of ENTA is JANUS HENDERSON GROUP PLC with $58.0B in shares.

Is institutional ownership of ENTA increasing or decreasing?

This quarter, 6 institutions opened new positions in ENTA and 7 closed their positions.