Who Owns Fulcrum Therapeutics, Inc. (FULC)?Hedge Fund & Institutional Holders

$7.54-0.10 (-1.25%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

1.366789119043672e+296%

QoQ Change in Holders

+8 / -3

Price History

$2.51$5.53$8.55$11.58$14.60Sep 24Jun 25Mar 26

FULC — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Point72 Asset Management, L.P.New Position+2.4M+$27.0B
SUVRETTA CAPITAL MANAGEMENT, LLCIncreased+1.2M+$24.7B
Siren, L.L.C.New Position+1.9M+$22.1B
First Turn Management, LLCNew Position+1.9M+$21.4B
Aberdeen Group plcIncreased+1.1M+$12.9B
ADAR1 Capital Management, LLCIncreased+912K+$11.0B
Vestal Point Capital, LPNew Position+950K+$10.7B
GREAT POINT PARTNERS LLCNew Position+800K+$9.0B
D. E. Shaw & Co., Inc.Increased+464K+$7.7B
CITADEL ADVISORS LLCIncreased+352K+$5.1B
SILVERARC CAPITAL MANAGEMENT, LLCNew Position+395K+$4.5B
Sio Capital Management, LLCNew Position+382K+$4.3B
Invesco Ltd.Increased+293K+$3.6B
DRIEHAUS CAPITAL MANAGEMENT LLCNew Position+243K+$2.8B
Connor, Clark & Lunn Investment Management Ltd.Increased+198K+$2.5B

FULC — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
RA CAPITAL MANAGEMENT, L.P.Decreased-4.2M-$94.0B
ROYAL BANK OF CANADADecreased-997K-$9.2B
BOOTHBAY FUND MANAGEMENT, LLCDecreased-161K-$6.2B
ADAGE CAPITAL PARTNERS GP, L.L.C.Decreased-732K-$3.4B
Schonfeld Strategic Advisors LLCDecreased-350K-$3.4B
BALYASNY ASSET MANAGEMENT L.P.Decreased-480K-$3.3B
GOLDMAN SACHS GROUP INCDecreased-262K-$2.4B
RENAISSANCE TECHNOLOGIES LLCDecreased-231K-$2.3B
UBS Group AGDecreased-198K-$1.6B
MILLENNIUM MANAGEMENT LLCDecreased-96K-$1.4B
J. Goldman & Co LPClosed Position-135K-$1.2B
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLCClosed Position-112K-$1.0B
DIMENSIONAL FUND ADVISORS LPDecreased-248K-$950.8M
BRIDGEWAY CAPITAL MANAGEMENT, LLCClosed Position-95K-$877.7M
ALLIANCEBERNSTEIN L.P.Decreased-59K-$686.2M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1SUVRETTA CAPITAL MANAGEMENT, LLC6,561,111$74.2B1.52%Share
2TCG Crossover Management, LLC5,250,000$59.4B1.97%Share
3Nantahala Capital Management, LLC4,293,346$48.6B1.61%Share
4Point72 Asset Management, L.P.2,398,232$27.0B30.19%Share
5Siren, L.L.C.1,950,000$22.1B0.66%Share
6First Turn Management, LLC1,892,683$21.4B2.45%Share
7ADAGE CAPITAL PARTNERS GP, L.L.C.1,700,000$19.0B28.76%Share
8D. E. Shaw & Co., Inc.1,434,152$16.0B8.77%Share
9Aberdeen Group plc1,254,027$14.2B21.96%Share
10ADAR1 Capital Management, LLC1,253,749$14.2B1.03%Share
11CITADEL ADVISORS LLC1,171,689$13.0B1.95%Share
12DIMENSIONAL FUND ADVISORS LP983,191$11.0B2.31%Share
13Vestal Point Capital, LP950,000$10.7B0.37%Share
14BALYASNY ASSET MANAGEMENT L.P.970,439$10.0B12.69%Share
15GREAT POINT PARTNERS LLC800,000$9.0B2.93%Share
16NORTHERN TRUST CORP543,628$6.0B0.76%Share
17Connor, Clark & Lunn Investment Management Ltd.582,377$6.0B15.74%Share
18D. E. Shaw & Co., Inc.479,603$5.0B2.74%Share
19SILVERARC CAPITAL MANAGEMENT, LLC394,650$4.5B0.62%Share
20SILVERARC CAPITAL MANAGEMENT, LLC391,900$4.4B0.62%Call
21Invesco Ltd.390,018$4.4B0.68%Share
22Sio Capital Management, LLC382,000$4.3B0.68%Share
23CHARLES SCHWAB INVESTMENT MANAGEMENT INC388,896$4.0B0.62%Share
24DEUTSCHE BANK AG\286,972$3.0B0.98%Share
25DRIEHAUS CAPITAL MANAGEMENT LLC243,388$2.8B18.69%Share
26Catalio Capital Management, LP201,301$2.3B0.40%Share
27Nicholas Investment Partners, LP182,961$2.1B0.15%Share
28BANK OF AMERICA CORP /DE/212,931$2.0B0.15%Share
29GOLDMAN SACHS GROUP INC223,645$2.0B0.25%Share
30Simplify Asset Management Inc.159,674$1.8B29.47%Share
31SummitTX Capital, L.P.138,143$1.6B0.05%Share
32UBS Group AG101,676$1.1B0.19%Share
33PRINCIPAL FINANCIAL GROUP INC95,813$1.1B0.55%Share
34Exome Asset Management LLC92,055$1.0B0.50%Share
35SUSQUEHANNA INTERNATIONAL GROUP, LLP140,500$1.0B0.12%Call
36SUSQUEHANNA INTERNATIONAL GROUP, LLP110,800$1.0B0.12%Put
37WELLINGTON MANAGEMENT GROUP LLP98,119$1.0B0.18%Share
38AMERIPRISE FINANCIAL INC100,675$1.0B0.23%Share
39FIDUCIARY TRUST CO136,555$1.0B11.37%Share
40WELLS FARGO & COMPANY/MN166,395$1.0B0.18%Share
41AMERICAN CENTURY COMPANIES INC157,672$1.0B0.50%Share
42Nuveen, LLC112,203$1.0B0.26%Share
43Jump Financial, LLC92,200$1.0B12.29%Share
44GOLDMAN SACHS GROUP INC100,234$1.0B0.12%Share
45BARCLAYS PLC132,541$1.0B0.24%Share
46ADAR1 Capital Management, LLC65,000$735.0M0.05%Call
47Integrated Quantitative Investments LLC62,522$707.0M0.15%Share
48Burkehill Global Management, LP50,000$565.0M0.04%Share
49STRS OHIO49,300$557.0M2.08%Share
50HSBC HOLDINGS PLC43,262$497.0M0.28%Share

FULC Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025170$439.0B+66
Q3 2025104$390.6B-6
Q2 2025110$280.7B-7
Q1 2025117$131.5B+3
Q4 2024114$196.8B+3
Q3 2024111$5.1T+7
Q2 2024104$3.1T-4
Q1 2024108$6.9T—

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As of Q4 2025, 50 institutional investors hold FULC (Fulcrum Therapeutics, Inc.). The largest holder is SUVRETTA CAPITAL MANAGEMENT, LLC with $74.2B in shares. This quarter, 8 institutions opened new positions and 3 closed their positions.

Frequently Asked Questions

How many hedge funds own FULC?

As of Q4 2025, 50 institutional investors report holding FULC (Fulcrum Therapeutics, Inc.) in their 13F filings.

Who is the largest institutional holder of FULC?

The largest institutional holder of FULC is SUVRETTA CAPITAL MANAGEMENT, LLC with $74.2B in shares.

Is institutional ownership of FULC increasing or decreasing?

This quarter, 8 institutions opened new positions in FULC and 3 closed their positions.