Who Owns Maze Therapeutics, Inc. (MAZE)?Hedge Fund & Institutional Holders

$50.35-1.49 (-2.86%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

3.2875790188079185e+284%

QoQ Change in Holders

+9 / -6

Price History

$7.57$18.64$29.70$40.77$51.84Jan 25Aug 25Mar 26

MAZE — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
JANUS HENDERSON GROUP PLCIncreased+2.4M+$110.5B
Bellevue Group AGNew Position+888K+$36.8B
VR Adviser, LLCIncreased+318K+$32.2B
FMR LLCIncreased+73K+$29.0B
Caligan Partners LPNew Position+550K+$22.8B
CITADEL ADVISORS LLCNew Position+448K+$18.0B
ArrowMark Colorado Holdings LLCIncreased+222K+$17.7B
EVENTIDE ASSET MANAGEMENT, LLCNew Position+324K+$13.4B
WASHINGTON UNIVERSITYNew Position+281K+$11.6B
TCG Crossover Management, LLCNew Position+174K+$7.2B
HighVista Strategies LLCNew Position+170K+$7.0B
ADAR1 Capital Management, LLCIncreased+153K+$6.8B
MILLENNIUM MANAGEMENT LLCNew Position+154K+$6.0B
STEMPOINT CAPITAL LPNew Position+126K+$5.2B
Ensign Peak Advisors, IncIncreased+115K+$5.2B

MAZE — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
TRV GP IV, LLCDecreased-1.6M-$157.3B
Matrix Capital Management Company, LPDecreased-1.2M-$42.9B
General Catalyst Group Management, LLCClosed Position-1.0M-$26.9B
Ikarian Capital, LLCDecreased-96K-$19.2B
Alphabet Inc.Decreased-1.0M-$5.0B
Octagon Capital Advisors LPClosed Position-178K-$4.6B
BALYASNY ASSET MANAGEMENT L.P.Decreased-235K-$3.2B
Schonfeld Strategic Advisors LLCDecreased-66K-$3.0B
Nantahala Capital Management, LLCClosed Position-93K-$2.4B
HARVARD MANAGEMENT CO INCClosed Position-92K-$2.4B
RENAISSANCE TECHNOLOGIES LLCDecreased-59K-$1.2B
ALLIANCEBERNSTEIN L.P.Decreased-27K-$558.4M
SUSQUEHANNA INTERNATIONAL GROUP, LLPClosed Position-16K-$419.2M
WINTON GROUP LtdClosed Position-14K-$375.6M
TWO SIGMA INVESTMENTS, LPDecreased-4K-$289.1M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Frazier Life Sciences Management, L.P.4,567,274$189.2B5.08%Share
2ARCH Venture Management, LLC4,120,053$170.7B26.19%Share
3JANUS HENDERSON GROUP PLC3,142,587$130.0B0.06%Share
4VR Adviser, LLC1,548,569$64.2B3.17%Share
5Alphabet Inc.1,388,583$57.5B2.23%Share
6Woodline Partners LP1,035,229$42.0B0.16%Share
7TRV GP V, LLC950,800$39.4B9.18%Share
8Logos Global Management LP950,000$39.4B2.38%Share
9Bellevue Group AG887,708$36.8B0.70%Share
10ArrowMark Colorado Holdings LLC767,383$31.8B0.70%Share
11Casdin Capital, LLC758,857$31.4B1.95%Share
12FMR LLC588,156$24.0B0.00%Share
13Caligan Partners LP550,191$22.8B1.88%Share
14Foresite Capital Management IV, LLC522,657$21.7B9.43%Share
15HHLR ADVISORS, LTD.457,535$19.0B0.61%Share
16CITADEL ADVISORS LLC448,217$18.0B0.00%Share
17DRIEHAUS CAPITAL MANAGEMENT LLC378,015$15.7B0.11%Share
18EVENTIDE ASSET MANAGEMENT, LLC324,041$13.4B0.21%Share
19WASHINGTON UNIVERSITY280,802$11.6B5.88%Share
20BALYASNY ASSET MANAGEMENT L.P.199,212$8.0B0.01%Share
21Alyeska Investment Group, L.P.196,124$8.0B0.02%Share
22ADAR1 Capital Management, LLC179,532$7.4B0.54%Share
23TCG Crossover Management, LLC173,816$7.2B0.24%Share
24Ensign Peak Advisors, Inc185,794$7.0B0.01%Share
25CHARLES SCHWAB INVESTMENT MANAGEMENT INC175,969$7.0B0.00%Share
26NORTHERN TRUST CORP172,721$7.0B0.00%Share
27HighVista Strategies LLC170,353$7.0B1.80%Share
28MILLENNIUM MANAGEMENT LLC154,470$6.0B0.00%Share
29STEMPOINT CAPITAL LP125,877$5.2B0.89%Share
30FMR LLC140,449$5.0B0.00%Share
31Invesco Ltd.114,655$4.8B0.00%Share
32Integral Health Asset Management, LLC100,000$4.1B0.21%Share
33AMERIPRISE FINANCIAL INC96,688$4.0B0.00%Share
34GOLDMAN SACHS GROUP INC106,145$4.0B0.00%Share
35Freestone Grove Partners LP118,876$4.0B0.03%Share
36SummitTX Capital, L.P.69,560$2.9B0.09%Share
37OSAIC HOLDINGS, INC.59,762$2.0B0.00%Share
38RAYMOND JAMES FINANCIAL INC66,447$2.0B0.00%Share
39Nuveen, LLC51,590$2.0B0.00%Share
40FRANKLIN RESOURCES INC52,640$2.0B0.00%Share
41Cinctive Capital Management LP29,134$1.2B0.07%Share
42UBS Group AG28,453$1.2B0.00%Share
43WELLINGTON MANAGEMENT GROUP LLP41,013$1.0B0.00%Share
44AQR CAPITAL MANAGEMENT LLC26,854$1.0B0.00%Share
45XTX Topco Ltd33,021$1.0B0.03%Share
46ALLIANCEBERNSTEIN L.P.33,220$1.0B0.00%Share
47RENAISSANCE TECHNOLOGIES LLC27,100$1.0B0.00%Share
48MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.31,295$1.0B0.00%Share
49BARCLAYS PLC39,508$1.0B0.00%Share
50GILDER GAGNON HOWE & CO LLC23,282$964.0M0.01%Share

MAZE Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025141$1.1T+60
Q3 202581$824.0B+17
Q2 202564$395.7B-4
Q1 202568$395.8B—

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As of Q4 2025, 50 institutional investors hold MAZE (Maze Therapeutics, Inc.). The largest holder is Frazier Life Sciences Management, L.P. with $189.2B in shares. This quarter, 9 institutions opened new positions and 6 closed their positions.

Frequently Asked Questions

How many hedge funds own MAZE?

As of Q4 2025, 50 institutional investors report holding MAZE (Maze Therapeutics, Inc.) in their 13F filings.

Who is the largest institutional holder of MAZE?

The largest institutional holder of MAZE is Frazier Life Sciences Management, L.P. with $189.2B in shares.

Is institutional ownership of MAZE increasing or decreasing?

This quarter, 9 institutions opened new positions in MAZE and 6 closed their positions.