Who Owns Personalis, Inc. (PSNL)?Hedge Fund & Institutional Holders

$6.75+0.17 (+2.50%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

2.6619694619439255e+280%

QoQ Change in Holders

+11 / -1

Price History

$3.00$5.06$7.13$9.19$11.25Sep 24Jun 25Mar 26

PSNL — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
AMERIPRISE FINANCIAL INCIncreased+6.0M+$46.1B
AIGH Capital Management LLCNew Position+2.9M+$23.1B
Aberdeen Group plcIncreased+862K+$10.3B
PFM Health Sciences, LPNew Position+806K+$6.4B
NEXT CENTURY GROWTH INVESTORS LLCNew Position+624K+$5.0B
HOWLAND CAPITAL MANAGEMENT LLCNew Position+547K+$4.4B
Sumitomo Mitsui Trust Group, Inc.New Position+518K+$4.1B
STATE OF MICHIGAN RETIREMENT SYSTEMNew Position+494K+$3.9B
Portolan Capital Management, LLCNew Position+379K+$3.0B
Wellington Shields & Co., LLCNew Position+292K+$2.3B
IQ EQ FUND MANAGEMENT (IRELAND) LtdNew Position+268K+$2.1B
FIRST MANHATTAN CO. LLC.New Position+374K+$2.0B
TD ASSET MANAGEMENT INCIncreased+217K+$1.6B
ORACLE INVESTMENT MANAGEMENT INCIncreased+110K+$1.2B
D.A. DAVIDSON & CO.New Position+146K+$1.2B

PSNL — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
MILLENNIUM MANAGEMENT LLCClosed Position-1.2M-$7.9B
RENAISSANCE TECHNOLOGIES LLCDecreased-360K-$3.0B
GOLDMAN SACHS GROUP INCDecreased-232K-$1.7B
ROYAL BANK OF CANADADecreased-75K-$1.0B
LPL Financial LLCDecreased-2K-$873.3M
Brooklyn Investment GroupDecreased-99K-$723.0M
NORTHERN TRUST CORPDecreased-39K-$567.5M
XTX Topco LtdDecreased-43K-$539.3M
RHUMBLINE ADVISERSDecreased-10K-$483.2M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.Decreased-8K-$421.6M
TWO SIGMA INVESTMENTS, LPDecreased-24K-$370.1M
STIFEL FINANCIAL CORPDecreased-34K-$313.0M
SUSQUEHANNA INTERNATIONAL GROUP, LLPDecreased-13K-$283.9M
HSBC HOLDINGS PLCDecreased-41K-$236.0M
MetLife Investment Management, LLCDecreased-11K-$194.3M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Merck & Co., Inc.14,044,943$111.8B40.47%Share
2ARK Investment Management LLC7,879,087$62.7B0.42%Share
3AMERIPRISE FINANCIAL INC3,507,345$27.0B0.01%Share
4Aberdeen Group plc3,249,895$25.9B0.04%Share
5AMERIPRISE FINANCIAL INC2,615,607$20.0B0.00%Share
6AIGH Capital Management LLC2,114,209$16.8B4.07%Share
7KENNEDY CAPITAL MANAGEMENT LLC1,712,652$13.6B0.29%Share
8Blue Water Life Science Advisors, LP1,676,300$13.3B8.37%Share
9PFM Health Sciences, LP805,817$6.4B0.64%Share
10AIGH Capital Management LLC785,791$6.3B1.51%Share
11DIMENSIONAL FUND ADVISORS LP860,367$6.0B0.00%Share
12NEXT CENTURY GROWTH INVESTORS LLC624,363$5.0B0.35%Share
13HOWLAND CAPITAL MANAGEMENT LLC547,115$4.4B0.17%Share
14Amova Asset Management Americas, Inc.518,441$4.1B0.05%Share
15Sumitomo Mitsui Trust Group, Inc.518,441$4.1B0.00%Share
16STATE OF MICHIGAN RETIREMENT SYSTEM493,798$3.9B0.02%Share
17Portolan Capital Management, LLC379,197$3.0B0.16%Share
18ORACLE INVESTMENT MANAGEMENT INC339,343$2.7B1.61%Share
19UBS Group AG301,555$2.4B0.00%Share
20Wellington Shields & Co., LLC292,489$2.3B0.57%Share
21IQ EQ FUND MANAGEMENT (IRELAND) Ltd267,674$2.1B0.15%Share
22GOLDMAN SACHS GROUP INC293,705$2.0B0.00%Share
23FIRST MANHATTAN CO. LLC.373,822$2.0B0.01%Share
24TD ASSET MANAGEMENT INC271,876$2.0B0.00%Share
25NORTHERN TRUST CORP346,917$2.0B0.00%Share
26Nuveen, LLC308,680$2.0B0.00%Share
27Bruce & Co., Inc.233,000$1.9B0.57%Share
28D.A. DAVIDSON & CO.145,507$1.2B0.01%Share
29AMERIPRISE FINANCIAL INC163,399$1.0B0.00%Share
30Williams Jones Wealth Management, LLC.134,072$1.0B0.01%Share
31CHARLES SCHWAB INVESTMENT MANAGEMENT INC158,170$1.0B0.00%Share
32POLEN CAPITAL MANAGEMENT LLC50,705$403.0M0.00%Share
33GROUP ONE TRADING LLC36,300$288.0M0.00%Call
34Invesco Ltd.19,011$151.0M0.00%Share
35AXQ CAPITAL, LP14,965$119.0M0.03%Share
36Invesco Ltd.13,096$104.0M0.00%Share
37US BANCORP \DE\12,768$101.0M0.00%Share
38Scientech Research LLC12,402$98.0M0.06%Share
39HSBC HOLDINGS PLC10,473$84.0M0.00%Share
40Lightspeed Management Company, L.L.C.8,160,734$65.0M4.65%Share
41Invesco Ltd.7,768$61.0M0.00%Share
42US BANCORP \DE\7,294$58.0M0.00%Share
43GROUP ONE TRADING LLC6,400$50.0M0.00%Put
44Caitong International Asset Management Co., Ltd5,536$44.0M0.12%Share
45INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC3,900$31.0M0.00%Share
46UBS Group AG3,483$27.0M0.00%Share
47VANGUARD GROUP INC2,876,807$22.0M0.00%Share
48BlackRock, Inc.2,472,531$19.0M0.00%Share
49Farther Finance Advisors, LLC2,489$19.0M0.00%Share
50Berbice Capital Management LLC320$18.0M0.01%Share

PSNL Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025126$361.5B+34
Q3 202592$284.5B+1
Q2 202591$206.4B-13
Q1 2025104$182.9B+0
Q4 2024104$258.1B+32
Q3 202472$1.9T+12
Q2 202460$127.0B-2
Q1 202462$26.0T—

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As of Q4 2025, 50 institutional investors hold PSNL (Personalis, Inc.). The largest holder is Merck & Co., Inc. with $111.8B in shares. This quarter, 11 institutions opened new positions and 1 closed their positions.

Frequently Asked Questions

How many hedge funds own PSNL?

As of Q4 2025, 50 institutional investors report holding PSNL (Personalis, Inc.) in their 13F filings.

Who is the largest institutional holder of PSNL?

The largest institutional holder of PSNL is Merck & Co., Inc. with $111.8B in shares.

Is institutional ownership of PSNL increasing or decreasing?

This quarter, 11 institutions opened new positions in PSNL and 1 closed their positions.