Who Owns PTC Therapeutics, Inc. (PTCT)?Hedge Fund & Institutional Holders

$66.70+2.20 (+3.41%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

Infinity%

QoQ Change in Holders

+3 / -5

Price History

$34.99$47.80$60.62$73.44$86.25Sep 24Jun 25Mar 26

PTCT — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
JANUS HENDERSON GROUP PLCIncreased+1.1M+$135.3B
FMR LLCIncreased+69K+$125.9B
TORONTO DOMINION BANKIncreased+892K+$114.8B
UBS Group AGIncreased+512K+$45.5B
Woodline Partners LPIncreased+466K+$36.5B
PRINCIPAL FINANCIAL GROUP INCNew Position+479K+$36.4B
JUPITER ASSET MANAGEMENT LTDNew Position+361K+$27.4B
FRANKLIN RESOURCES INCIncreased+130K+$26.0B
PUBLIC SECTOR PENSION INVESTMENT BOARDNew Position+325K+$24.0B
GOLDMAN SACHS GROUP INCIncreased+147K+$22.2B
DRIEHAUS CAPITAL MANAGEMENT LLCIncreased+4K+$16.8B
Hood River Capital Management LLCIncreased+7K+$15.1B
Boston PartnersIncreased+126K+$14.8B
Invesco Ltd.Increased+121K+$13.8B
CHARLES SCHWAB INVESTMENT MANAGEMENT INCIncreased+32K+$11.9B

PTCT — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
ARMISTICE CAPITAL, LLCDecreased-475K-$201.1B
MILLENNIUM MANAGEMENT LLCDecreased-1.0M-$63.8B
Pacer Advisors, Inc.Decreased-268K-$31.4B
Qube Research & Technologies LtdClosed Position-431K-$26.4B
CITADEL ADVISORS LLCDecreased-577K-$19.2B
Ikarian Capital, LLCDecreased-162K-$17.2B
Man Group plcDecreased-249K-$15.3B
WELLINGTON MANAGEMENT GROUP LLPDecreased-1.1M-$11.9B
Sofinnova Investments, Inc.Closed Position-187K-$11.5B
RENAISSANCE TECHNOLOGIES LLCDecreased-320K-$10.9B
HSBC HOLDINGS PLCDecreased-166K-$10.0B
VOLORIDGE INVESTMENT MANAGEMENT, LLCClosed Position-160K-$9.8B
Candriam S.C.A.Closed Position-146K-$9.0B
ADAGE CAPITAL PARTNERS GP, L.L.C.Decreased-150K-$7.9B
GROUP ONE TRADING LLCClosed Position-113K-$7.0B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1JANUS HENDERSON GROUP PLC4,742,903$360.0B161.21%Share
2TORONTO DOMINION BANK4,138,215$314.0B463.45%Share
3WELLINGTON MANAGEMENT GROUP LLP3,288,809$249.0B43.63%Share
4TANG CAPITAL MANAGEMENT LLC1,500,000$113.9B5.63%Share
5FRANKLIN RESOURCES INC1,282,301$97.0B23.80%Share
6CITADEL ADVISORS LLC1,150,888$87.0B13.07%Share
7DRIEHAUS CAPITAL MANAGEMENT LLC1,136,188$86.3B586.22%Share
8Point72 Asset Management, L.P.1,128,551$85.0B95.06%Share
9Hood River Capital Management LLC1,003,075$76.2B835.29%Share
10FMR LLC927,443$70.0B3.57%Share
11D. E. Shaw & Co., Inc.897,416$68.0B37.28%Share
12D. E. Shaw & Co., Inc.847,575$64.0B35.08%Share
13GOLDMAN SACHS GROUP INC773,022$58.0B7.15%Share
14BANK OF AMERICA CORP /DE/757,442$57.0B4.15%Share
15CHARLES SCHWAB INVESTMENT MANAGEMENT INC734,933$55.0B8.55%Share
16NORTHERN TRUST CORP670,242$50.0B6.37%Share
17RENAISSANCE TECHNOLOGIES LLC607,589$46.0B71.36%Share
18DIMENSIONAL FUND ADVISORS LP583,982$44.0B9.23%Share
19Woodline Partners LP571,553$43.0B166.61%Share
20Nuveen, LLC534,690$40.0B10.47%Share
21Boston Partners487,977$37.0B38.31%Share
22UBS Group AG484,630$36.8B5.97%Share
23PRINCIPAL FINANCIAL GROUP INC474,541$36.0B18.40%Share
24UBS Group AG461,917$35.1B5.69%Share
25MANUFACTURERS LIFE INSURANCE COMPANY, THE426,506$32.0B26.30%Share
26Rockefeller Capital Management L.P.405,127$30.0B54.01%Share
27ARROWSTREET CAPITAL, LIMITED PARTNERSHIP406,410$30.0B17.57%Share
28Invesco Ltd.369,560$28.1B4.30%Share
29FMR LLC368,774$28.0B1.43%Share
30PANAGORA ASSET MANAGEMENT INC359,837$27.0B95.69%Share
31AQR CAPITAL MANAGEMENT LLC331,842$25.0B13.11%Share
32WELLINGTON MANAGEMENT GROUP LLP338,404$25.0B4.38%Share
33FMR LLC316,951$24.0B1.22%Share
34PUBLIC SECTOR PENSION INVESTMENT BOARD324,636$24.0B80.58%Share
35Ensign Peak Advisors, Inc280,572$21.0B37.09%Share
36JUPITER ASSET MANAGEMENT LTD270,849$20.6B164.68%Share
37GOLDMAN SACHS GROUP INC247,249$18.0B2.22%Share
38MACKENZIE FINANCIAL CORP236,909$18.0B21.32%Share
39Legal & General Group Plc228,531$17.0B3.77%Share
40BANK OF AMERICA CORP /DE/232,228$17.0B1.24%Share
41DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main220,847$16.0B13.82%Share
42BANK OF AMERICA CORP /DE/215,466$16.0B1.16%Share
43BARCLAYS PLC219,127$16.0B3.84%Share
44Boxer Capital Management, LLC200,000$15.2B3.33%Share
45VOYA INVESTMENT MANAGEMENT LLC208,211$15.0B14.79%Share
46RHUMBLINE ADVISERS207,950$15.0B12.13%Share
47PRUDENTIAL FINANCIAL INC164,785$12.0B14.49%Share
48DEUTSCHE BANK AG\164,535$12.0B3.91%Share
49JPMORGAN CHASE & CO168,396$12.0B0.75%Share
50Universal- Beteiligungs- und Servicegesellschaft mbH151,401$11.5B18.67%Share

PTCT Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025344$3.1T+123
Q3 2025221$3.2T-14
Q2 2025235$2.0T-28
Q1 2025263$3.1T+28
Q4 2024235$3.4T+62
Q3 2024173$29.1T+4
Q2 2024169$34.1T+18
Q1 2024151$1570.9T—

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As of Q4 2025, 50 institutional investors hold PTCT (PTC Therapeutics, Inc.). The largest holder is JANUS HENDERSON GROUP PLC with $360.0B in shares. This quarter, 3 institutions opened new positions and 5 closed their positions.

Frequently Asked Questions

How many hedge funds own PTCT?

As of Q4 2025, 50 institutional investors report holding PTCT (PTC Therapeutics, Inc.) in their 13F filings.

Who is the largest institutional holder of PTCT?

The largest institutional holder of PTCT is JANUS HENDERSON GROUP PLC with $360.0B in shares.

Is institutional ownership of PTCT increasing or decreasing?

This quarter, 3 institutions opened new positions in PTCT and 5 closed their positions.