Who Owns Summit Therapeutics Inc. (SMMT)?Hedge Fund & Institutional Holders

$16.29+0.17 (+1.05%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

3.533891458935497e+300%

QoQ Change in Holders

+6 / -5

Price History

$13.85$19.56$25.27$30.99$36.70Sep 24Jun 25Mar 26

SMMT — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
FMR LLCIncreased+4.4M+$231.8B
CITADEL ADVISORS LLCIncreased+2.3M+$37.8B
APEIRON CAPITAL LtdNew Position+1.3M+$22.9B
TD ASSET MANAGEMENT INCIncreased+668K+$9.9B
TWO SIGMA INVESTMENTS, LPIncreased+553K+$9.5B
Polymer Capital Management (HK) LTDIncreased+604K+$8.0B
MILLENNIUM MANAGEMENT LLCIncreased+349K+$5.5B
D. E. Shaw & Co., Inc.Increased+285K+$4.3B
AQR CAPITAL MANAGEMENT LLCIncreased+170K+$2.1B
HSBC HOLDINGS PLCNew Position+99K+$1.7B
TEMA ETFS LLCNew Position+96K+$1.7B
AXQ CAPITAL, LPIncreased+64K+$1.1B
Assenagon Asset Management S.A.New Position+60K+$1.0B
Wealth Management Partners, LLCNew Position+59K+$1.0B
Aquatic Capital Management LLCNew Position+60K+$1.0B

SMMT — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Fiera Capital CorpClosed Position-762K-$15.7B
Polar Capital Holdings PlcClosed Position-746K-$15.4B
NOMURA HOLDINGS INCDecreased-507K-$12.7B
TANG CAPITAL MANAGEMENT LLCClosed Position-550K-$11.4B
UBS Group AGDecreased-408K-$11.2B
Aberdeen Group plcDecreased-212K-$7.3B
SUSQUEHANNA INTERNATIONAL GROUP, LLPClosed Position-247K-$5.1B
BARCLAYS PLCDecreased-137K-$4.8B
SUPERSTRING CAPITAL MANAGEMENT LPClosed Position-197K-$4.1B
BALYASNY ASSET MANAGEMENT L.P.Decreased-145K-$4.0B
ROYAL BANK OF CANADADecreased-183K-$3.8B
FIRST TRUST ADVISORS LPDecreased-143K-$3.5B
VOYA INVESTMENT MANAGEMENT LLCDecreased-90K-$3.2B
WELLS FARGO & COMPANY/MNDecreased-62K-$3.0B
CITIGROUP INCDecreased-30K-$2.3B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1BAKER BROS. ADVISORS LP36,391,063$636.5B3726.76%Share
2FMR LLC9,807,044$171.0B8.72%Share
3FMR LLC3,531,491$61.0B3.11%Share
4CITADEL ADVISORS LLC1,860,490$32.0B4.81%Share
5SUSQUEHANNA INTERNATIONAL GROUP, LLP1,802,700$31.0B3.57%Put
6SUSQUEHANNA INTERNATIONAL GROUP, LLP1,463,300$25.0B2.88%Call
7Polymer Capital Management (HK) LTD1,421,155$24.9B3.54%Share
8APEIRON CAPITAL Ltd1,309,241$22.9B26.48%Share
9TD ASSET MANAGEMENT INC1,205,272$21.0B16.89%Share
10Aberdeen Group plc927,171$16.2B25.11%Share
11CHARLES SCHWAB INVESTMENT MANAGEMENT INC892,629$15.0B2.33%Share
12UBS Group AG797,674$14.0B2.26%Share
13Rock Springs Capital Management LP710,000$12.4B0.64%Share
14TWO SIGMA INVESTMENTS, LP578,248$10.0B14.10%Share
15CITADEL ADVISORS LLC615,218$10.0B1.50%Share
16NOMURA HOLDINGS INC542,234$9.0B11.98%Share
17Candriam S.C.A.540,662$9.0B44.82%Share
18NORTHERN TRUST CORP524,604$9.0B1.15%Share
19MILLENNIUM MANAGEMENT LLC469,017$8.0B3.36%Share
20BANK OF AMERICA CORP /DE/401,713$7.0B0.51%Share
21MANUFACTURERS LIFE INSURANCE COMPANY, THE440,953$7.0B5.75%Share
22D. E. Shaw & Co., Inc.415,284$7.0B3.84%Share
23CITADEL ADVISORS LLC417,500$7.0B1.05%Put
24Invesco Ltd.389,386$6.8B1.04%Share
25QVT Financial LP360,524$6.3B0.54%Share
26Affinity Asset Advisors, LLC350,000$6.1B0.35%Put
27GOLDMAN SACHS GROUP INC352,524$6.0B0.74%Share
28AQR CAPITAL MANAGEMENT LLC357,863$6.0B3.15%Share
29Sculptor Capital LP356,900$6.0B61.77%Put
30Sculptor Capital LP356,900$6.0B61.77%Share
31BARCLAYS PLC338,308$5.0B1.20%Share
32Rafferty Asset Management, LLC287,810$5.0B17.27%Share
33CITADEL ADVISORS LLC318,800$5.0B0.75%Call
34Skandinaviska Enskilda Banken AB (publ)338,363$5.0B20.05%Share
35Caption Management, LLC240,000$4.2B28.78%Call
36SCHRODER INVESTMENT MANAGEMENT GROUP251,391$4.0B3.03%Share
37DEUTSCHE BANK AG\230,000$4.0B1.30%Share
38DIMENSIONAL FUND ADVISORS LP261,144$4.0B0.84%Share
39GROUP ONE TRADING LLC226,300$4.0B6.91%Call
40Nuveen, LLC173,379$3.0B0.79%Share
41Woodline Partners LP214,507$3.0B11.62%Share
42GROUP ONE TRADING LLC168,600$2.9B5.15%Put
43Caption Management, LLC125,000$2.2B14.99%Put
44RHUMBLINE ADVISERS121,341$2.0B1.62%Share
45SIMPLEX TRADING, LLC144,700$2.0B1.13%Call
46GOLDMAN SACHS GROUP INC133,042$2.0B0.25%Share
47Centiva Capital, LP100,000$1.7B14.23%Call
48TEMA ETFS LLC95,782$1.7B0.13%Share
49ADAR1 Capital Management, LLC91,869$1.6B0.12%Share
50IMC-Chicago, LLC83,700$1.5B0.53%Call

SMMT Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025207$1.2T+36
Q3 2025171$1.1T-23
Q2 2025194$1.3T-7
Q1 2025201$1.2T+10
Q4 2024191$834.1B+57
Q3 2024134$16.2T+28
Q2 2024106$4.5T+23
Q1 202483$670.6T—

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As of Q4 2025, 50 institutional investors hold SMMT (Summit Therapeutics Inc.). The largest holder is BAKER BROS. ADVISORS LP with $636.5B in shares. This quarter, 6 institutions opened new positions and 5 closed their positions.

Frequently Asked Questions

How many hedge funds own SMMT?

As of Q4 2025, 50 institutional investors report holding SMMT (Summit Therapeutics Inc.) in their 13F filings.

Who is the largest institutional holder of SMMT?

The largest institutional holder of SMMT is BAKER BROS. ADVISORS LP with $636.5B in shares.

Is institutional ownership of SMMT increasing or decreasing?

This quarter, 6 institutions opened new positions in SMMT and 5 closed their positions.