Who Owns SOPHiA GENETICS S.A. (SOPH)?Hedge Fund & Institutional Holders

$4.62+0.01 (+0.33%)HealthcareNASDAQ

Institutional Holders

49

as of Q4 2025

Total Institutional Value

$3.170700017368e+133T

% of Float Held

1.3318722406442956e+229%

QoQ Change in Holders

+10 / -7

Price History

$2.66$3.38$4.09$4.80$5.52Sep 24Jun 25Mar 26

SOPH — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
BANQUE PICTET & CIE SANew Position+2.2M+$10.3B
Alta Wealth Advisors LLCNew Position+1.4M+$6.6B
PRINCIPAL FINANCIAL GROUP INCNew Position+1.4M+$6.5B
ROYCE & ASSOCIATES LPNew Position+430K+$2.0B
1492 Capital Management LLCNew Position+208K+$972.0M
UBS Group AGIncreased+47K+$214.8M
POLEN CAPITAL MANAGEMENT LLCNew Position+22K+$101.0M
Archon Capital Management LLCIncreased+14K+$28.1M
ASSETMARK, INCIncreased+566+$1.4M
Bank Pictet & Cie (Europe) AGNew Position+255K+$1.2M
Silverberg Bernstein Capital Management LLCIncreased+1K+$637K
Green Alpha Advisors, LLCNew Position+46K+$213K
PERKINS CAPITAL MANAGEMENT INCNew Position+11K+$49K
FEDERATED HERMES, INC.New Position+188K+$0
GEODE CAPITAL MANAGEMENT, LLCIncreased+680+$0

SOPH — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
MILLENNIUM MANAGEMENT LLCDecreased-100K-$1.1B
Ensign Peak Advisors, IncDecreased-13K-$929.1M
Rathbones Group PLCDecreased-2K-$772.7M
DIMENSIONAL FUND ADVISORS LPClosed Position-31K-$148.2M
CITADEL ADVISORS LLCClosed Position-12K-$58.6M
Squarepoint Ops LLCClosed Position-10K-$48.7M
Zurcher Kantonalbank (Zurich Cantonalbank)Decreased-3K-$16.0M
Tower Research Capital LLC (TRC)Closed Position-491-$2.3M
Groupe la FrancaiseClosed Position-120-$569K
THOMPSON SIEGEL & WALMSLEY LLCClosed Position-30K-$142K
FNY Investment Advisers, LLCDecreased-29K-$138K
PRINCIPAL SECURITIES, INC.Closed Position-394-$1K
SIMPLEX TRADING, LLCDecreased-995-$0

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1GENERATION INVESTMENT MANAGEMENT LLP6,789,560$31.7B0.22%Share
2AKRE CAPITAL MANAGEMENT LLC3,719,140$17.4B0.19%Share
3BANQUE PICTET & CIE SA2,208,280$10.3B0.06%Share
4Alta Wealth Advisors LLC1,409,160$6.6B2.20%Share
5PRINCIPAL FINANCIAL GROUP INC1,399,442$6.5B0.00%Share
6Archon Capital Management LLC441,413$2.1B1.17%Share
7ROYCE & ASSOCIATES LP430,257$2.0B0.02%Share
81492 Capital Management LLC208,345$972.0M0.37%Share
9UBS Group AG54,946$256.0M0.00%Share
10Silverberg Bernstein Capital Management LLC47,815$223.0M0.13%Share
11GROUP ONE TRADING LLC40,400$188.0M0.00%Call
12POLEN CAPITAL MANAGEMENT LLC21,738$101.0M0.00%Share
13UBS Group AG6,955$32.0M0.00%Share
14ASSETMARK, INC4,687$21.0M0.00%Share
15Zurcher Kantonalbank (Zurich Cantonalbank)3,755$17.0M0.00%Share
16Compagnie Lombard Odier SCmA1,055$4.0M0.00%Share
17Bank Pictet & Cie (Europe) AG255,200$1.2M0.02%Share
18Rathbones Group PLC160,133$747K0.00%Share
19Green Alpha Advisors, LLC45,660$213K0.20%Share
20FNY Investment Advisers, LLC16,010$74K0.02%Share
21PERKINS CAPITAL MANAGEMENT INC10,500$49K0.04%Share
22XTX Topco Ltd11,760$00.00%Share
23Russell Investments Group, Ltd.59$00.00%Share
24Ensign Peak Advisors, Inc182,414$00.00%Share
25ROYAL BANK OF CANADA600$00.00%Share
26PNC FINANCIAL SERVICES GROUP, INC.370$00.00%Share
27BlackRock, Inc.107$00.00%Share
28BlackRock, Inc.2,985$00.00%Share
29BlackRock, Inc.1,994$00.00%Share
30MORGAN STANLEY23,180$00.00%Share
31MORGAN STANLEY24,867$00.00%Share
32GSA CAPITAL PARTNERS LLP24,967$00.00%Share
33ACADIAN ASSET MANAGEMENT LLC5,911$00.00%Share
34Pathstone Holdings, LLC32,203$00.00%Share
35GEODE CAPITAL MANAGEMENT, LLC92,596$00.00%Share
36SIMPLEX TRADING, LLC31$00.00%Share
37RENAISSANCE TECHNOLOGIES LLC83,000$00.00%Share
38MILLENNIUM MANAGEMENT LLC125,458$00.00%Share
39SUSQUEHANNA INTERNATIONAL GROUP, LLP30,511$00.00%Share
40EDMOND DE ROTHSCHILD HOLDING S.A.203,334$00.00%Share
41Quadrature Capital Ltd11,649$00.00%Share
42BANK OF AMERICA CORP /DE/5,540$00.00%Share
43BANK OF AMERICA CORP /DE/12$00.00%Share
44FEDERATED HERMES, INC.75,071$00.00%Share
45FEDERATED HERMES, INC.112,606$00.00%Share
46GOLDMAN SACHS GROUP INC28,660$00.00%Share
47OSAIC HOLDINGS, INC.1,000$00.00%Share
48SBI Securities Co., Ltd.41$00.00%Share
49United Financial Planning Group LLC170$00.00%Share

SOPH Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202542$78.2B+10
Q3 202532$56.8B+5
Q2 202527$49.0B-5
Q1 202532$51.6B-1
Q4 202433$740.1B+4
Q3 202429$9.0T+0
Q2 202429$11.3T+1
Q1 202428$1.2T—

Similar Stocks by Institutional Ownership

LLY

Eli Lilly and Company

JNJ

Johnson & Johnson

ABBV

AbbVie Inc.

NVS

Novartis AG

AZN

AstraZeneca PLC

MRK

Merck & Co., Inc.

UNH

UnitedHealth Group Incorporated

AMGN

Amgen Inc.

As of Q4 2025, 49 institutional investors hold SOPH (SOPHiA GENETICS S.A.). The largest holder is GENERATION INVESTMENT MANAGEMENT LLP with $31.7B in shares. This quarter, 10 institutions opened new positions and 7 closed their positions.

Frequently Asked Questions

How many hedge funds own SOPH?

As of Q4 2025, 49 institutional investors report holding SOPH (SOPHiA GENETICS S.A.) in their 13F filings.

Who is the largest institutional holder of SOPH?

The largest institutional holder of SOPH is GENERATION INVESTMENT MANAGEMENT LLP with $31.7B in shares.

Is institutional ownership of SOPH increasing or decreasing?

This quarter, 10 institutions opened new positions in SOPH and 7 closed their positions.