BAKER BROS. ADVISORS LP Q2 2016 Filing

Filed August 15, 2016

Portfolio Value

$9.5T

Holdings

135

Report Date

Q2 2016

Filing Type

13F-HR

All Holdings (135 positions)

#StockSharesValue% PortfolioType
101
Mast Therapeutics, Inc.
3,868,026$1.8B0.02%
102
MediWound Ltd.
226,000$1.8B0.02%
103
AMRNAmarin Corporation plc
801,860$1.7B0.02%
104
QUREuniQure N.V.
230,000$1.7B0.02%
105
ENTAEnanta Pharmaceuticals, Inc.
75,357$1.7B0.02%
106
CytRx Corporation
659,995$1.5B0.02%
107
KPTIEURKaryopharm Therapeutics Inc.
216,990$1.5B0.02%
108
ASMBAssembly Biosciences, Inc.
250,000$1.4B0.01%
109
GW Pharmaceuticals plc
15,000$1.4B0.01%
110
ISIIonis Pharmaceuticals, Inc.
57,140$1.3B0.01%
111
CLLSCellectis S.A.
50,000$1.3B0.01%
112
Immune Design Corp.
148,937$1.2B0.01%
113
DVAXDynavax Technologies Corporation
75,000$1.1B0.01%
114
Tenax Therapeutics, Inc.
420,000$1.1B0.01%
115
SCYXEURSCYNEXIS, Inc.
467,600$1.0B0.01%
116
Affimed N.V.
400,000$992.0M0.01%
117
XLRNAcceleron Pharma Inc.
28,765$977.0M0.01%
118
Palatin Technologies, Inc.
2,050,000$905.0M0.01%
119
ADAPYAdaptimmune Therapeutics plc
100,000$815.0M0.01%
120
ALDXAldeyra Therapeutics, Inc.
142,000$808.0M0.01%
121
Five Prime Therapeutics, Inc.
19,247$796.0M0.01%
122
ALNYAlnylam Pharmaceuticals, Inc.
11,340$629.0M0.01%
123
I9DNArbutus Biopharma Corporation
180,582$628.0M0.01%
124
Ritter Pharmaceuticals, Inc.
400,000$612.0M0.01%
125
Synta Pharmaceuticals Corp.
2,021,728$526.0M0.01%
126
BioDelivery Sciences International, Inc.
210,021$496.0M0.01%
127
Windtree Therapeutics, Inc.
254,973$492.0M0.01%
128
CMRXEURChimerix, Inc.
115,216$453.0M0.00%
129
ProNAi Therapeutics, Inc.
200,000$398.0M0.00%
130
Foundation Medicine, Inc.
20,892$390.0M0.00%
131
Achaogen, Inc.
100,000$379.0M0.00%
132
CCXIEURChemoCentryx, Inc.
49,064$220.0M0.00%
133
La Jolla Pharmaceutical Company
13,746$220.0M0.00%
134
BGMS 6 PERPCyclacel Pharmaceuticals, Inc.
13,253$83.0M0.00%
135
BioTime, Inc.
20,084$9.0M0.00%
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