Samsara BioCapital, LLC
CIK: 0001744967Latest portfolio: $969.3M · Q4 2025
Holdings
21
Total Value
$969.3M
New Positions
3
Closed Positions
9
Top Holdings
| # | Stock | Shares | Value | % Portfolio | Change | Type |
|---|---|---|---|---|---|---|
| 1 | SRRKSCHOLAR ROCK HLDG CORP | 6,897,652 | $303.8M | 31.35% | +1.3M | |
| 2 | MLYSMINERALYS THERAPEUTICS INC | 5,871,018 | $213.1M | 21.98% | -392,133 | |
| 3 | KLRSKALARIS THERAPEUTICS INC | 12,948,081 | $109.3M | 11.27% | +1.5M | |
| 4 | SEPNSEPTERNA INC | 3,149,128 | $87.8M | 9.06% | — | |
| 5 | ALMSALUMIS INC | 5,756,984 | $56.2M | 5.80% | +956K | |
| 6 | NGNENEUROGENE INC | 1,717,127 | $35.4M | 3.65% | — | |
| 7 | IVAINVENTIVA SA | 5,194,805 | $24.2M | 2.49% | NEW | |
| 8 | GOSSGOSSAMER BIO INC | 7,222,559 | $22.4M | 2.31% | +1.1M | |
| 9 | UPBUPSTREAM BIO INC | 736,047 | $20.0M | 2.06% | -226,107 | |
| 10 | AQSTAQUESTIVE THERAPEUTICS INC | 2,500,000 | $16.1M | 1.67% | — | |
| 11 | JBIOJADE BIOSCIENCES INC | 968,798 | $14.9M | 1.54% | +438K | |
| 12 | VTVTVTV THERAPEUTICS INC | 298,496 | $11.9M | 1.23% | -75,965 | |
| 13 | RANIRANI THERAPEUTICS HLDGS INC | 8,500,000 | $11.5M | 1.18% | NEW | |
| 14 | PVLAPALVELLA THERAPEUTICS INC NE | 104,817 | $11.0M | 1.13% | -104,817 | |
| 15 | ABVXABIVAX SA | 75,442 | $10.2M | 1.05% | — | |
| 16 | XFORX4 PHARMACEUTICALS INC | 1,960,000 | $7.8M | 0.81% | NEW | |
| 17 | NKTXNKARTA INC | 3,507,666 | $6.5M | 0.67% | -260,369 | |
| 18 | ACLXARCELLX INC | 60,873 | $4.0M | 0.41% | -20,292 | |
| 19 | STROSUTRO BIOPHARMA INC | 204,503 | $2.4M | 0.24% | NEW | |
| 20 | CTNMCONTINEUM THERAPEUTICS INC | 72,245 | $825K | 0.09% | -498,897 | |
| 21 | NUVB/WSNUVATION BIO INC | 124,119 | $40K | 0.00% | -9,214 |
Quarterly Changes
Sector Breakdown
Healthcare0.1% ($3.0384121305910924e+87T)
Unknown0.0% ($40K)
Filing History
Fund Information
Samsara BioCapital, LLC is an institutional investment manager that files 13F reports with the SEC. As of the Q4 2025 filing, the fund reported a portfolio valued at $969.3M across 21 holdings. The largest position is SCHOLAR ROCK HLDG CORP (SRRK), representing 31.3% of the portfolio. Compared to the previous quarter, the fund opened 4 new positions and closed 10 positions. 13F filings are required quarterly disclosures that provide transparency into the holdings of institutional investment managers with at least $100 million in qualifying assets.