SR ONE CAPITAL MANAGEMENT, LP

CIK: 0001910264SEC EDGAR →

Portfolio Value

$706.4M

Holdings

13

As of

Q4 2025

New Positions

0

Closed Positions

1

Top 10 Holdings

RankStockSharesValue% of Portfolio
1

Zenas BioPharma, Inc

5,037,854$182.9M
25.90%
2

Arcellx, Inc.

2,346,630$153.0M
21.66%
3

CRISPR Therapeutics AG

2,038,763$106.9M
15.14%
4

Design Therapeutics, Inc.

6,526,476$61.2M
8.67%
5

Mineralys Therapeutics Inc.

1,563,966$56.8M
8.03%
6

ARS Pharmaceuticals, Inc.

4,012,903$46.8M
6.62%
7

ORIC Pharmaceuticals, Inc.

4,514,929$37.8M
5.34%
8

Alumis Inc.

1,959,896$19.1M
2.71%
9

Oruka Therapeutics, Inc

430,330$13.0M
1.85%
10

Oculis Holding AG

641,022$12.8M
1.81%

Quarterly Changes

Top Buys

ZBIO↑ Increased
$73.9M
OCS↑ Increased
$7.1M
RARENEW
$3.2M

Top Sells

MLYS↓ Decreased
$23.4M

New Positions (1)

$3.2M · 138K shares

Sector Breakdown

Sector# HoldingsValue%
Healthcare13$706.4M100.0%