Who Owns Milestone Pharmaceuticals Inc. (MIST)?Hedge Fund & Institutional Holders

$1.68-0.07 (-3.99%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$5.00000030420003e+213T

% of Float Held

3.3483339698545435e+269%

QoQ Change in Holders

+9 / -7

Price History

$0.65$1.23$1.80$2.38$2.95Sep 24Jun 25Mar 26

MIST — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Simplify Asset Management Inc.New Position+1.5M+$3.0B
TWO SIGMA INVESTMENTS, LPIncreased+848K+$1.7B
Stonepine Capital Management, LLCNew Position+663K+$1.3B
TWO SIGMA ADVISERS, LPIncreased+386K+$531.9M
SUSQUEHANNA INTERNATIONAL GROUP, LLPIncreased+387K+$486.5M
GROUP ONE TRADING LLCIncreased+188K+$380.0M
ADAR1 Capital Management, LLCNew Position+100K+$202.0M
UBS Group AGIncreased+94K+$196.9M
GUARDIAN WEALTH ADVISORS, LLC / NCIncreased+53K+$110.6M
Scientech Research LLCNew Position+30K+$60.0M
Invesco Ltd.New Position+22K+$44.0M
Stephenson & Company, Inc.New Position+20K+$40.0M
SJS Investment Consulting Inc.New Position+15K+$30.0M
Strategic Family Wealth Counselors, L.L.C.New Position+13K+$25.0M
Eaton Financial Holdings Company, LLCNew Position+13K+$25.0M

MIST — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Propel Bio Management, LLCDecreased-1.0M-$10.2B
ADAGE CAPITAL PARTNERS GP, L.L.C.Decreased-4.2M-$9.0B
ORBIMED ADVISORS LLCClosed Position-3.2M-$6.4B
Affinity Asset Advisors, LLCClosed Position-667K-$1.3B
CITADEL ADVISORS LLCDecreased-159K-$1.0B
GOLDMAN SACHS GROUP INCClosed Position-357K-$713.1M
Quadrature Capital LtdClosed Position-223K-$448.1M
XTX Topco LtdDecreased-15K-$374.6M
ROYAL BANK OF CANADADecreased-137K-$287.0M
MORGAN STANLEYDecreased-2.2M-$4.9M
Wealthspire Advisors, LLCClosed Position-1K-$2.3M
SPHERA FUNDS MANAGEMENT LTD.Closed Position-820K-$1.6M
HRT FINANCIAL LPClosed Position-139K-$277K
STATE STREET CORPDecreased-345-$44K
BANK OF AMERICA CORP /DE/Decreased-15K-$32K

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1ADAGE CAPITAL PARTNERS GP, L.L.C.2,810,037$5.0B0.01%Share
2Simplify Asset Management Inc.1,506,405$3.0B0.05%Share
3TWO SIGMA INVESTMENTS, LP1,514,461$3.0B0.00%Share
4Boxer Capital Management, LLC666,666$1.3B0.29%Share
5Stonepine Capital Management, LLC662,666$1.3B0.98%Share
6SUSQUEHANNA INTERNATIONAL GROUP, LLP643,300$1.0B0.00%Share
7TWO SIGMA ADVISERS, LP619,592$1.0B0.00%Share
8SUSQUEHANNA INTERNATIONAL GROUP, LLP532,900$1.0B0.00%Put
9TORONTO DOMINION BANK750,000$1.0B0.00%Share
10UBS Group AG437,534$883.0M0.00%Share
11GROUP ONE TRADING LLC374,500$756.0M0.00%Put
12GUARDIAN WEALTH ADVISORS, LLC / NC263,200$531.0M0.03%Share
13GROUP ONE TRADING LLC195,099$394.0M0.00%Share
14GROUP ONE TRADING LLC165,400$334.0M0.00%Call
15ADAR1 Capital Management, LLC100,100$202.0M0.01%Share
16Cascades Capital Asset Management, LLC77,510$156.0M0.07%Share
17UBS Group AG52,602$106.0M0.00%Share
18Scientech Research LLC30,124$60.0M0.04%Share
19Bay Rivers Group28,861$58.0M0.02%Share
20Safeguard Investment Advisory Group, LLC25,044$50.0M0.01%Share
21Invesco Ltd.21,893$44.0M0.00%Share
22Stephenson & Company, Inc.20,000$40.0M0.02%Share
23SJS Investment Consulting Inc.15,000$30.0M0.00%Share
24Beta Wealth Group, Inc.14,127$28.0M0.01%Share
25Strategic Family Wealth Counselors, L.L.C.12,675$25.0M0.01%Share
26Eaton Financial Holdings Company, LLC12,750$25.0M0.01%Share
27Bronte Capital Management Pty Ltd.10,414$21.0M0.00%Share
28Taylor Financial Group, Inc.10,000$20.0M0.01%Share
29INTEGRAL INVESTMENT ADVISORS, INC.10,000$20.0M0.00%Share
30Propel Bio Management, LLC4,118,321$8.3M7.10%Share
31US BANCORP \DE\3,200$6.0M0.00%Share
32UBS Group AG1,732$3.0M0.00%Share
33MARSHALL WACE, LLP1,617,063$3.0M0.00%Share
34Pathstone Holdings, LLC1,017,040$2.0M0.01%Share
35Lion Point Capital, LP755,000$1.5M7.89%Share
36MORGAN STANLEY731,539$1.0M0.00%Share
37JANE STREET GROUP, LLC581,846$1.0M0.00%Share
38Valeo Financial Advisors, LLC130,699$264K0.00%Share
39SG Americas Securities, LLC97,375$197K0.00%Share
40October Effect Ltd52,100$105K0.12%Share
41Secure Asset Management, LLC10,000$20K0.00%Share
42RTW INVESTMENTS, LP2,506,102$5K0.00%Share
43Graham Capital Management, L.P.133,620$00.00%Share
44Ancora Advisors LLC10,000$00.00%Share
45SUSQUEHANNA INTERNATIONAL GROUP, LLP73,200$00.00%Call
46Tower Research Capital LLC (TRC)8,980$00.00%Share
47BANK OF AMERICA CORP /DE/841$00.00%Share
48NORTHERN TRUST CORP39,258$00.00%Share
49JONES FINANCIAL COMPANIES LLLP16,000$00.00%Share
50Focus Partners Wealth36,000$00.00%Share

MIST Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202576$19.4B+23
Q3 202553$51.3B+19
Q2 202534$13.1B-10
Q1 202544$9.4B-3
Q4 202447$47.2B+12
Q3 202435$173.6B+2
Q2 202433$142.7B+0
Q1 202433$180.8B

Similar Stocks by Institutional Ownership

As of Q4 2025, 50 institutional investors hold MIST (Milestone Pharmaceuticals Inc.). The largest holder is ADAGE CAPITAL PARTNERS GP, L.L.C. with $5.0B in shares. This quarter, 9 institutions opened new positions and 7 closed their positions.

Frequently Asked Questions

How many hedge funds own MIST?

As of Q4 2025, 50 institutional investors report holding MIST (Milestone Pharmaceuticals Inc.) in their 13F filings.

Who is the largest institutional holder of MIST?

The largest institutional holder of MIST is ADAGE CAPITAL PARTNERS GP, L.L.C. with $5.0B in shares.

Is institutional ownership of MIST increasing or decreasing?

This quarter, 9 institutions opened new positions in MIST and 7 closed their positions.