Who Owns Soleno Therapeutics, Inc. (SLNO)?Hedge Fund & Institutional Holders

$34.19-2.55 (-6.94%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

Infinity%

QoQ Change in Holders

+11 / -8

Price History

$33.76$47.44$61.12$74.81$88.49Sep 24Jun 25Mar 26

SLNO — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
FMR LLCIncreased+80K+$371.5B
Woodline Partners LPIncreased+841K+$32.7B
EMERALD ADVISERS, LLCNew Position+413K+$19.1B
Assenagon Asset Management S.A.New Position+384K+$17.8B
Integral Health Asset Management, LLCNew Position+325K+$15.0B
Logos Global Management LPNew Position+300K+$13.9B
Aberdeen Group plcNew Position+287K+$13.3B
Penn Capital Management Company, LLCNew Position+276K+$12.8B
EMERALD MUTUAL FUND ADVISERS TRUSTNew Position+232K+$10.8B
SUSQUEHANNA INTERNATIONAL GROUP, LLPIncreased+228K+$9.9B
Clark Capital Management Group, Inc.New Position+180K+$8.0B
NEW YORK STATE COMMON RETIREMENT FUNDNew Position+185K+$8.0B
BANK OF AMERICA CORP /DE/Increased+46K+$8.0B
Eagle Health Investments LPNew Position+135K+$6.3B
PEREGRINE CAPITAL MANAGEMENT LLCNew Position+120K+$5.5B

SLNO — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Vivo Capital, LLCDecreased-1.4M-$112.6B
ADAGE CAPITAL PARTNERS GP, L.L.C.Closed Position-1.4M-$94.7B
Holocene Advisors, LPClosed Position-997K-$67.4B
Invesco Ltd.Decreased-626K-$60.9B
WESTFIELD CAPITAL MANAGEMENT CO LPClosed Position-899K-$60.8B
Capital World InvestorsDecreased-679K-$49.7B
Commodore Capital LPDecreased-150K-$35.7B
BALYASNY ASSET MANAGEMENT L.P.Decreased-433K-$34.7B
EVENTIDE ASSET MANAGEMENT, LLCClosed Position-467K-$31.6B
Siren, L.L.C.Closed Position-467K-$31.6B
SAMLYN CAPITAL, LLCClosed Position-466K-$31.5B
Tri Locum Partners LPClosed Position-451K-$30.5B
Polar Capital Holdings PlcDecreased-54K-$28.5B
TimesSquare Capital Management, LLCClosed Position-378K-$25.5B
Caption Management, LLCDecreased-328K-$23.1B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1JANUS HENDERSON GROUP PLC7,048,897$326.0B145.99%Share
2FMR LLC6,339,279$293.0B14.94%Share
3WELLINGTON MANAGEMENT GROUP LLP2,961,418$137.0B24.01%Share
4Avoro Capital Advisors LLC2,900,000$134.3B1319.69%Share
5FMR LLC1,473,375$68.0B3.47%Share
6Nantahala Capital Management, LLC1,314,002$60.8B2.01%Share
7MILLENNIUM MANAGEMENT LLC1,236,321$57.0B23.97%Share
8Commodore Capital LP1,200,000$55.6B3.70%Share
9Polar Capital Holdings Plc1,136,929$52.0B200.95%Share
10Woodline Partners LP1,111,778$51.0B197.61%Share
11Vivo Capital, LLC894,909$41.4B2.68%Share
12GOLDMAN SACHS GROUP INC883,921$40.0B4.93%Share
13Invesco Ltd.840,684$38.9B5.97%Share
14FRANKLIN RESOURCES INC815,524$37.0B9.08%Share
15Hood River Capital Management LLC618,005$28.6B313.68%Share
16Artia Global Partners LP533,698$24.7B3.50%Share
17Nantahala Capital Management, LLC502,000$23.2B0.77%Call
18SCHRODER INVESTMENT MANAGEMENT GROUP449,550$20.0B15.16%Share
19EMERALD ADVISERS, LLC412,651$19.1B0.59%Share
20GREAT POINT PARTNERS LLC400,000$18.5B6.00%Share
21CHARLES SCHWAB INVESTMENT MANAGEMENT INC401,186$18.0B2.80%Share
22Assenagon Asset Management S.A.384,166$17.8B24.48%Share
23Catalio Capital Management, LP360,340$16.7B2.95%Share
24NORTHERN TRUST CORP348,085$16.0B2.04%Share
25SUSQUEHANNA INTERNATIONAL GROUP, LLP357,300$16.0B1.84%Put
26Caption Management, LLC342,500$15.9B108.74%Put
27Integral Health Asset Management, LLC325,000$15.0B0.75%Share
28Logos Global Management LP300,000$13.9B0.84%Share
29Aberdeen Group plc287,456$13.3B20.61%Share
30Penn Capital Management Company, LLC275,782$12.8B1.02%Share
31PFM Health Sciences, LP247,893$11.5B1.14%Share
32Rock Springs Capital Management LP247,053$11.4B0.59%Share
33SUSQUEHANNA INTERNATIONAL GROUP, LLP244,358$11.0B1.27%Share
34WELLINGTON MANAGEMENT GROUP LLP255,295$11.0B1.93%Share
35SUSQUEHANNA INTERNATIONAL GROUP, LLP254,900$11.0B1.27%Call
36CITIGROUP INC255,400$11.0B4.85%Call
37EMERALD MUTUAL FUND ADVISERS TRUST232,485$10.8B0.52%Share
38BALYASNY ASSET MANAGEMENT L.P.227,751$10.0B12.69%Share
39CITADEL ADVISORS LLC231,335$10.0B1.50%Share
40Alyeska Investment Group, L.P.217,500$10.0B28.25%Share
41SummitTX Capital, L.P.211,727$9.8B0.30%Share
42CITADEL ADVISORS LLC197,500$9.0B1.35%Put
43NEW YORK STATE COMMON RETIREMENT FUND185,317$8.0B10.68%Share
44Skandinaviska Enskilda Banken AB (publ)187,475$8.0B32.09%Share
45Clark Capital Management Group, Inc.180,250$8.0B49.16%Share
46Ally Bridge Group (NY) LLC168,029$7.8B8.10%Share
47UBS Group AG166,054$7.7B1.25%Share
48BARCLAYS PLC157,666$7.0B1.68%Share
49FMR LLC158,700$7.0B0.36%Share
50Granahan Investment Management, LLC137,592$6.4B0.27%Share

SLNO Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025246$1.9T+52
Q3 2025194$2.5T+0
Q2 2025194$3.3T-22
Q1 2025216$3.2T+51
Q4 2024165$1.9T+43
Q3 2024122$13.9T+16
Q2 2024106$14.4T+19
Q1 202487$394.0T—

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As of Q4 2025, 50 institutional investors hold SLNO (Soleno Therapeutics, Inc.). The largest holder is JANUS HENDERSON GROUP PLC with $326.0B in shares. This quarter, 11 institutions opened new positions and 8 closed their positions.

Frequently Asked Questions

How many hedge funds own SLNO?

As of Q4 2025, 50 institutional investors report holding SLNO (Soleno Therapeutics, Inc.) in their 13F filings.

Who is the largest institutional holder of SLNO?

The largest institutional holder of SLNO is JANUS HENDERSON GROUP PLC with $326.0B in shares.

Is institutional ownership of SLNO increasing or decreasing?

This quarter, 11 institutions opened new positions in SLNO and 8 closed their positions.