Who Owns VYNE Therapeutics Inc. (VYNE)?Hedge Fund & Institutional Holders

$0.60+0.01 (+2.13%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$9.427395805482901e+61T

% of Float Held

1.1923559452804304e+215%

QoQ Change in Holders

+13 / -3

Price History

$0.29$1.29$2.28$3.28$4.28Sep 24Jun 25Mar 26

VYNE — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Anson Funds Management LPNew Position+1.3M+$739K
Nantahala Capital Management, LLCNew Position+1.0M+$580K
T3 Companies, LLCNew Position+945K+$548K
KVP Capital Advisors, LPNew Position+501K+$290K
ADAR1 Capital Management, LLCNew Position+254K+$147K
Virtu Financial LLCNew Position+25K+$15K
FNY Investment Advisers, LLCNew Position+25K+$14K
CITADEL ADVISORS LLCNew Position+31K+$0
CWM, LLCNew Position+500+$0
Hurley Capital, LLCNew Position+561+$0
Centerpoint Advisors, LLCNew Position+350+$0
XTX Topco LtdNew Position+79K+$0
COMMONWEALTH EQUITY SERVICES, LLCNew Position+18K+$0
GSA CAPITAL PARTNERS LLPIncreased+18K+$-12K
ACADIAN ASSET MANAGEMENT LLCIncreased+192K+$-148K

VYNE — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
BAKER BROS. ADVISORS LPClosed Position-851K-$285.2M
ACORN CAPITAL ADVISORS, LLCDecreased-585K-$199.4M
Ikarian Capital, LLCDecreased-25K-$97.0M
TWO SIGMA INVESTMENTS, LPDecreased-788-$74.0M
JANE STREET GROUP, LLCDecreased-75K-$49.3M
BOOTHBAY FUND MANAGEMENT, LLCDecreased-25K-$35.7M
BRIDGEWAY CAPITAL MANAGEMENT, LLCClosed Position-77K-$25.8M
CORSAIR CAPITAL MANAGEMENT, L.P.Closed Position-50K-$16.8M
Tower Research Capital LLC (TRC)Decreased-30-$1.2M
MORGAN STANLEYDecreased-868-$305K

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Shay Capital LLC1,624,349$942K0.10%Share
2Anson Funds Management LP1,274,386$739K0.07%Share
3Nantahala Capital Management, LLC1,000,000$580K0.02%Share
4T3 Companies, LLC945,000$548K0.68%Share
5KVP Capital Advisors, LP500,551$290K0.28%Share
6Ikarian Capital, LLC264,912$153K0.01%Share
7ADAR1 Capital Management, LLC253,791$147K0.01%Share
8VANGUARD GROUP INC183,443$106K0.00%Share
9VANGUARD GROUP INC130,098$75K0.00%Share
10Rangeley Capital, LLC100,000$58K0.05%Share
11UBS Group AG62,761$36K0.00%Share
12Virtu Financial LLC25,327$15K0.00%Share
13FNY Investment Advisers, LLC25,000$14K0.00%Share
14Harvest Investment Services, LLC11,059$6K0.00%Share
15ROYAL BANK OF CANADA2,440$00.00%Share
16TWO SIGMA INVESTMENTS, LP220,000$00.00%Share
17CITADEL ADVISORS LLC30,526$00.00%Share
18CWM, LLC500$00.00%Share
19SUSQUEHANNA INTERNATIONAL GROUP, LLP42,578$00.00%Share
20SUSQUEHANNA INTERNATIONAL GROUP, LLP57,763$00.00%Share
21TWO SIGMA ADVISERS, LP163,100$00.00%Share
22Tower Research Capital LLC (TRC)3,567$00.00%Share
23BOOTHBAY FUND MANAGEMENT, LLC81,371$00.00%Share
24BANK OF AMERICA CORP /DE/249$00.00%Share
25BANK OF AMERICA CORP /DE/1,334$00.00%Share
26BANK OF AMERICA CORP /DE/94$00.00%Share
27NORTHERN TRUST CORP23,110$00.00%Share
28GSA CAPITAL PARTNERS LLP53,961$00.00%Share
29MORGAN STANLEY5$00.00%Share
30MORGAN STANLEY38$00.00%Share
31BlackRock, Inc.44,404$00.00%Share
32BlackRock, Inc.1$00.00%Share
33JPMORGAN CHASE & CO138$00.00%Share
34JPMORGAN CHASE & CO8$00.00%Share
35Hurley Capital, LLC561$00.00%Share
36ACORN CAPITAL ADVISORS, LLC1,425$00.00%Share
37Truvestments Capital LLC25$00.00%Share
38ACADIAN ASSET MANAGEMENT LLC638,492$00.00%Share
39VANGUARD GROUP INC1,004$00.00%Share
40Newbridge Financial Services Group, Inc.10$00.00%Share
41MB, LEVIS & ASSOCIATES, LLC1,041$00.00%Share
42Centerpoint Advisors, LLC350$00.00%Share
43WELLS FARGO & COMPANY/MN65$00.00%Share
44COMMONWEALTH EQUITY SERVICES, LLC18,298$00.00%Share
45XTX Topco Ltd79,040$00.00%Share
46STATE STREET CORP15,765$00.00%Share
47JANE STREET GROUP, LLC13$00.00%Share
48JANE STREET GROUP, LLC72,343$00.00%Share
49GEODE CAPITAL MANAGEMENT, LLC204,366$00.00%Share
50GEODE CAPITAL MANAGEMENT, LLC20,786$00.00%Share

VYNE Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202540$3.7M+10
Q3 202530$1.2B-9
Q2 202539$13.0B+2
Q1 202537$11.3B+4
Q4 202433$23.3B+6
Q3 202427$9.6T+2
Q2 202425$9.8T-1
Q1 202426$12.8T

Similar Stocks by Institutional Ownership

As of Q4 2025, 50 institutional investors hold VYNE (VYNE Therapeutics Inc.). The largest holder is Shay Capital LLC with $942K in shares. This quarter, 13 institutions opened new positions and 3 closed their positions.

Frequently Asked Questions

How many hedge funds own VYNE?

As of Q4 2025, 50 institutional investors report holding VYNE (VYNE Therapeutics Inc.) in their 13F filings.

Who is the largest institutional holder of VYNE?

The largest institutional holder of VYNE is Shay Capital LLC with $942K in shares.

Is institutional ownership of VYNE increasing or decreasing?

This quarter, 13 institutions opened new positions in VYNE and 3 closed their positions.