ADAGE CAPITAL PARTNERS GP, L.L.C. Q4 2025 Filing

Filed February 17, 2026

Portfolio Value

$66.1B

Holdings

905

Report Date

Q4 2025

Filing Type

13F-HR

All Holdings (905 positions)

#	Stock	Shares	Value	% Portfolio
1	KOS 3.125 03/15/30KOSMOS ENERGY LTD	38,392,000	$15.0B	22.70%
2	NVDANVIDIA CORPORATION	22,258,110	$4.2B	6.28%
3	AAPLAPPLE INC	13,226,554	$3.6B	5.44%
4	MSFTMICROSOFT CORP	6,627,143	$3.2B	4.85%
5	AMZNAMAZON COM INC	9,064,760	$2.1B	3.17%
6	GOOGLALPHABET INC	5,253,800	$1.6B	2.49%
7	AVGOBROADCOM INC	4,222,056	$1.5B	2.21%
8	GOOGALPHABET INC	4,179,120	$1.3B	1.98%
9	TSLATESLA INC	2,472,800	$1.1B	1.68%
10	JPMJPMORGAN CHASE & CO.	2,428,466	$782.0M	1.18%
11	COPCONOCOPHILLIPS	7,037,277	$658.0M	1.00%
12	VVISA INC	1,507,340	$528.0M	0.80%
13	JNJJOHNSON & JOHNSON	2,210,913	$457.0M	0.69%
14	RPRXROYALTY PHARMA PLC	11,740,594	$453.0M	0.69%
15	WMTWALMART INC	3,873,326	$431.0M	0.65%
16	PGPROCTER AND GAMBLE CO	2,822,220	$404.0M	0.61%
17	NFLXNETFLIX INC	4,035,830	$378.0M	0.57%
18	PLTRPALANTIR TECHNOLOGIES INC	2,064,600	$366.0M	0.55%
19	HDHOME DEPOT INC	1,061,656	$365.0M	0.55%
20	ORCLORACLE CORP	1,870,116	$364.0M	0.55%
21	BACBANK AMERICA CORP	6,505,273	$357.0M	0.54%
22	ABBVABBVIE INC	1,508,715	$344.0M	0.52%
23	BABOEING CO	1,534,944	$333.0M	0.50%
24	XOMEXXON MOBIL CORP	2,661,722	$320.0M	0.48%
25	MUMICRON TECHNOLOGY INC	1,110,803	$317.0M	0.48%
26	DOVDOVER CORP	1,556,098	$303.0M	0.46%
27	CSCOCISCO SYS INC	3,907,721	$301.0M	0.46%
28	AMDADVANCED MICRO DEVICES INC	1,384,794	$296.0M	0.45%
29	UNHUNITEDHEALTH GROUP INC	864,352	$285.0M	0.43%
30	PRAXPRAXIS PRECISION MEDICINES I	965,313	$284.0M	0.43%
31	MRKMERCK & CO INC	2,687,850	$282.0M	0.43%
32	CNTACENTESSA PHARMACEUTICALS PLC	11,281,741	$282.0M	0.43%
33	CRMSALESFORCE INC	1,059,439	$280.0M	0.42%
34	GEGE AEROSPACE	886,363	$273.0M	0.41%
35	CVXCHEVRON CORP NEW	1,780,166	$271.0M	0.41%
36	IBMINTERNATIONAL BUSINESS MACHS	883,890	$261.0M	0.40%
37	WFCWELLS FARGO CO NEW	2,697,196	$251.0M	0.38%
38	KOCOCA COLA CO	3,425,082	$239.0M	0.36%
39	ROIVROIVANT SCIENCES LTD	10,677,894	$231.0M	0.35%
40	NSCNORFOLK SOUTHN CORP	798,093	$230.0M	0.35%
41	4I1PHILIP MORRIS INTL INC	1,406,954	$225.0M	0.34%
42	TERNTERNS PHARMACEUTICALS INC	5,550,000	$224.0M	0.34%
43	DISDISNEY WALT CO	1,961,725	$223.0M	0.34%
44	LRCXLAM RESEARCH CORP	1,291,620	$221.0M	0.33%
45	VNOMVIPER ENERGY INC	5,711,539	$220.0M	0.33%
46	HUBBHUBBELL INC	488,897	$217.0M	0.33%
47	OVVOVINTIV INC	5,462,109	$214.0M	0.32%
48	AONAON PLC	606,569	$214.0M	0.32%
49	ABTABBOTT LABS	1,681,202	$210.0M	0.32%
50	RTXRTX CORPORATION	1,142,869	$209.0M	0.32%
51	WMWASTE MGMT INC DEL	918,710	$201.0M	0.30%
52	BSXBOSTON SCIENTIFIC CORP	2,082,360	$198.0M	0.30%
53	FERGFERGUSON ENTERPRISES INC	889,472	$198.0M	0.30%
54	LINLINDE PLC	463,935	$197.0M	0.30%
55	RNAAVIDITY BIOSCIENCES INC	2,630,966	$189.0M	0.29%
56	JCIJOHNSON CTLS INTL PLC	1,555,271	$186.0M	0.28%
57	RVMDREVOLUTION MEDICINES INC	2,205,555	$175.0M	0.26%
58	SCHWSCHWAB CHARLES CORP	1,709,639	$170.0M	0.26%
59	WVEWAVE LIFE SCIENCES LTD	9,786,061	$166.0M	0.25%
60	EWEDWARDS LIFESCIENCES CORP	1,954,631	$166.0M	0.25%
61	DHRDANAHER CORPORATION	722,084	$165.0M	0.25%
62	MCDMCDONALDS CORP	541,602	$165.0M	0.25%
63	BACVERIZON COMMUNICATIONS INC	4,035,772	$164.0M	0.25%
64	AMATAPPLIED MATLS INC	641,726	$164.0M	0.25%
65	DWDMORGAN STANLEY	922,634	$163.0M	0.25%
66	DVNDEVON ENERGY CORP NEW	4,456,292	$163.0M	0.25%
67	TRVCCITIGROUP INC	1,399,186	$163.0M	0.25%
68	QCOMQUALCOMM INC	938,521	$160.0M	0.24%
69	TAT&T INC	6,407,539	$159.0M	0.24%
70	SRESEMPRA	1,754,370	$154.0M	0.23%
71	INTCINTEL CORP	4,070,054	$150.0M	0.23%
72	UBERUBER TECHNOLOGIES INC	1,818,000	$148.0M	0.22%
73	PEPPEPSICO INC	1,032,879	$148.0M	0.22%
74	APHAMPHENOL CORP NEW	1,092,620	$147.0M	0.22%
75	ACNACCENTURE PLC IRELAND	534,822	$143.0M	0.22%
76	MTDRMATADOR RES CO	3,365,997	$142.0M	0.21%
77	AXPAMERICAN EXPRESS CO	381,588	$141.0M	0.21%
78	CSXCSX CORP	3,832,708	$138.0M	0.21%
79	CVSCVS HEALTH CORP	1,721,266	$136.0M	0.21%
80	NOWSERVICENOW INC	891,900	$136.0M	0.21%
81	COFCAPITAL ONE FINL CORP	548,928	$133.0M	0.20%
82	SWXSOUTHWEST GAS HLDGS INC	1,648,496	$131.0M	0.20%
83	ROSTROSS STORES INC	712,586	$128.0M	0.19%
84	DDOMINION ENERGY INC	2,141,911	$125.0M	0.19%
85	VRTXVERTEX PHARMACEUTICALS INC	272,474	$123.0M	0.19%
86	TJXTJX COS INC NEW	802,548	$123.0M	0.19%
87	ADBEADOBE INC	352,878	$123.0M	0.19%
88	TXNTEXAS INSTRS INC	704,244	$122.0M	0.18%
89	MDTMEDTRONIC PLC	1,273,871	$122.0M	0.18%
90	CITHE CIGNA GROUP	438,151	$120.0M	0.18%
91	SDRLSEADRILL LTD	3,484,940	$120.0M	0.18%
92	ANETARISTA NETWORKS INC	917,200	$120.0M	0.18%
93	ARANTERO RESOURCES CORP	3,438,110	$118.0M	0.18%
94	CHRDCHORD ENERGY CORPORATION	1,243,850	$115.0M	0.17%
95	LOWLOWES COS INC	472,905	$114.0M	0.17%
96	CBCHUBB LIMITED	364,883	$113.0M	0.17%
97	WBDWARNER BROS DISCOVERY INC	3,923,383	$113.0M	0.17%
98	TVTXTRAVERE THERAPEUTICS INC	2,927,000	$111.0M	0.17%
99	BKHBLACK HILLS CORP	1,592,000	$110.0M	0.17%
100	RHCRH PLC	880,100	$109.0M	0.16%

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