ORBIMED ADVISORS LLC Q1 2018 Filing
Filed May 15, 2018
Portfolio Value
$8.1B
Holdings
133
Report Date
Q1 2018
Filing Type
13F-HR
All Holdings (133 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | ALXNALEXION PHARMACEUTICALS INC | 3,318,275 | $369.9B | 4585.78% | Call |
| 2 | REGNREGENERON PHARMACEUTICALS | 962,900 | $331.6B | 4111.26% | |
| 3 | VRTXVERTEX PHARMACEUTICALS INC | 1,854,600 | $302.3B | 3747.72% | |
| 4 | MRKMERCK & CO INC | 5,288,200 | $288.0B | 3571.47% | |
| 5 | BIIBBIOGEN INC | 1,040,400 | $284.9B | 3532.21% | |
| 6 | BSXBOSTON SCIENTIFIC CORP | 10,377,795 | $283.5B | 3515.34% | |
| 7 | BMYBRISTOL MYERS SQUIBB CO | 3,875,300 | $245.1B | 3039.12% | Call |
| 8 | CELGCELGENE CORP | 2,634,250 | $235.0B | 2913.74% | |
| 9 | ASNDASCENDIS PHARMA A S | 3,367,315 | $220.2B | 2730.50% | |
| 10 | AG8AGILENT TECHNOLOGIES INC | 2,836,900 | $189.8B | 2353.17% | |
| 11 | PBYIPUMA BIOTECHNOLOGY INC | 2,641,661 | $179.8B | 2228.88% | |
| 12 | —CLEMENTIA PHARMACEUTICALS IN | 10,425,225 | $157.9B | 1958.30% | |
| 13 | JAZZJAZZ PHARMACEUTICALS PLC | 1,040,100 | $157.0B | 1947.18% | |
| 14 | —ARMO BIOSCIENCES INC | 4,118,903 | $154.1B | 1910.52% | |
| 15 | ALNYALNYLAM PHARMACEUTICALS INC | 1,265,966 | $150.8B | 1869.46% | |
| 16 | ABBVABBVIE INC | 1,527,500 | $144.6B | 1792.60% | |
| 17 | EWEDWARDS LIFESCIENCES CORP | 1,024,600 | $143.0B | 1772.44% | |
| 18 | —WRIGHT MED GROUP N V | 6,852,068 | $135.9B | 1685.56% | |
| 19 | CLVSEURCLOVIS ONCOLOGY INC | 2,395,870 | $126.5B | 1568.48% | Call |
| 20 | —ALLERGAN PLC | 693,605 | $116.7B | 1447.28% | |
| 21 | NVROEURNEVRO CORP | 1,260,091 | $109.2B | 1354.10% | |
| 22 | —LOXO ONCOLOGY INC | 941,000 | $108.6B | 1346.06% | |
| 23 | AM6AMICUS THERAPEUTICS INC | 7,072,500 | $106.4B | 1318.87% | |
| 24 | —AUDENTES THERAPEUTICS INC | 3,522,100 | $105.8B | 1312.28% | |
| 25 | DVADAVITA INC | 1,559,600 | $102.8B | 1275.10% | |
| 26 | AERIEURAERIE PHARMACEUTICALS INC | 1,884,100 | $102.2B | 1267.31% | |
| 27 | THCTENET HEALTHCARE CORP | 4,189,300 | $101.6B | 1259.61% | |
| 28 | —SHIRE PLC | 650,308 | $97.2B | 1204.55% | |
| 29 | IOVAIOVANCE BIOTHERAPEUTICS INC | 5,548,326 | $93.8B | 1162.60% | |
| 30 | UHSUNIVERSAL HLTH SVCS INC | 772,900 | $91.5B | 1134.73% | |
| 31 | SEMSELECT MED HLDGS CORP | 5,074,200 | $87.5B | 1085.27% | |
| 32 | —MYLAN N V | 2,084,300 | $85.8B | 1063.96% | Call |
| 33 | —IMMUNOMEDICS INC | 5,710,774 | $83.4B | 1034.49% | |
| 34 | TMOTHERMO FISHER SCIENTIFIC INC | 389,400 | $80.4B | 996.82% | |
| 35 | ARRYEURARRAY BIOPHARMA INC | 4,900,900 | $80.0B | 991.70% | |
| 36 | AMGNAMGEN INC | 445,310 | $75.9B | 941.27% | |
| 37 | ACADACADIA PHARMACEUTICALS INC | 3,340,700 | $75.1B | 930.73% | |
| 38 | XTNTXTANT MED HLDGS INC | 9,207,012 | $72.6B | 900.69% | |
| 39 | GBTUSDGLOBAL BLOOD THERAPEUTICS IN | 1,466,530 | $70.8B | 878.25% | |
| 40 | CRVSCORVUS PHARMACEUTICALS INC | 5,967,584 | $68.8B | 853.12% | |
| 41 | ILMNILLUMINA INC | 284,500 | $67.3B | 833.96% | |
| 42 | IM8NINSMED INC | 2,927,891 | $65.9B | 817.53% | |
| 43 | VRAYQVIEWRAY INC | 9,458,567 | $60.8B | 754.09% | |
| 44 | —MAGELLAN HEALTH INC | 563,843 | $60.4B | 748.74% | |
| 45 | JNJJOHNSON & JOHNSON | 465,300 | $59.6B | 739.32% | |
| 46 | ONCBEIGENE LTD | 354,900 | $59.6B | 739.26% | |
| 47 | —BLUEBIRD BIO INC | 345,600 | $59.0B | 731.67% | |
| 48 | RYTMRHYTHM PHARMACEUTICALS INC | 2,901,295 | $57.7B | 715.86% | |
| 49 | KALAKALA PHARMACEUTICALS INC | 3,447,840 | $54.6B | 676.72% | |
| 50 | GLPGGALAPAGOS NV | 486,990 | $48.6B | 602.36% | |
| 51 | IRWDIRONWOOD PHARMACEUTICALS INC | 3,079,250 | $47.5B | 589.11% | Call |
| 52 | HCAHCA HEALTHCARE INC | 482,400 | $46.8B | 580.18% | |
| 53 | —RESTORBIO INC | 4,830,387 | $46.3B | 573.76% | |
| 54 | —ARSANIS INC | 1,868,966 | $42.8B | 530.44% | |
| 55 | LTHLIFEPOINT HEALTH INC | 902,825 | $42.4B | 526.12% | |
| 56 | SCPHSCPHARMACEUTICALS INC | 3,409,865 | $42.3B | 524.25% | |
| 57 | ISRGINTUITIVE SURGICAL INC | 102,000 | $42.1B | 522.10% | |
| 58 | ARGXARGENX SE | 500,000 | $40.2B | 498.68% | |
| 59 | SYKSTRYKER CORP | 236,300 | $38.0B | 471.47% | |
| 60 | PIRSPIERIS PHARMACEUTICALS INC | 5,550,000 | $37.9B | 469.31% | |
| 61 | ASMBASSEMBLY BIOSCIENCES INC | 721,166 | $35.4B | 439.39% | |
| 62 | —OBSEVA SA | 2,605,531 | $35.2B | 435.97% | |
| 63 | PFEPFIZER INC | 982,000 | $34.9B | 432.11% | |
| 64 | —ENVISION HEALTHCARE CORP | 875,400 | $33.6B | 417.12% | |
| 65 | CICIGNA CORPORATION | 192,300 | $32.3B | 399.94% | |
| 66 | HRTXHERON THERAPEUTICS INC | 1,139,800 | $31.5B | 390.04% | |
| 67 | DCPHEURDECIPHERA PHARMACEUTICALS IN | 1,532,900 | $30.7B | 380.88% | |
| 68 | TFXTELEFLEX INC | 117,000 | $29.8B | 369.90% | |
| 69 | SRPTSAREPTA THERAPEUTICS INC | 371,600 | $27.5B | 341.37% | Call |
| 70 | GILDGILEAD SCIENCES INC | 364,600 | $27.5B | 340.81% | |
| 71 | —RADIUS HEALTH INC | 762,900 | $27.4B | 339.96% | |
| 72 | NVLSEURALPINE IMMUNE SCIENCES INC | 3,298,516 | $26.4B | 327.18% | |
| 73 | EHTHEHEALTH INC | 1,834,700 | $26.3B | 325.53% | |
| 74 | NVONOVO-NORDISK A S | 530,000 | $26.1B | 323.65% | Call |
| 75 | VRNAVERONA PHARMA PLC | 1,250,396 | $25.0B | 310.07% | |
| 76 | SVASINOVAC BIOTECH LTD | 2,839,500 | $24.4B | 303.13% | |
| 77 | ABTABBOTT LABS | 394,100 | $23.6B | 292.79% | |
| 78 | INSM 1.75 01/15/25INSMED INC | 26,500,000 | $23.5B | 291.19% | |
| 79 | NTLAINTELLIA THERAPEUTICS INC | 1,113,000 | $23.5B | 291.04% | |
| 80 | INSYEURINSYS THERAPEUTICS INC NEW | 3,511,544 | $21.2B | 262.98% | |
| 81 | MDMEDNAX INC | 370,000 | $20.6B | 255.21% | |
| 82 | —NABRIVA THERAPEUTICS PLC | 3,919,600 | $19.7B | 244.46% | |
| 83 | CTIC1USDCTI BIOPHARMA CORP | 5,000,000 | $19.5B | 241.78% | |
| 84 | —SYNLOGIC INC | 2,029,996 | $19.0B | 236.09% | |
| 85 | SELBUSDSELECTA BIOSCIENCES INC | 1,842,797 | $18.8B | 232.83% | |
| 86 | XNCRXENCOR INC | 612,500 | $18.4B | 227.68% | |
| 87 | CHRSCOHERUS BIOSCIENCES INC | 1,466,800 | $16.2B | 200.96% | |
| 88 | —K2M GROUP HLDGS INC | 843,205 | $16.0B | 198.12% | |
| 89 | IMGNEURIMMUNOGEN INC | 1,504,270 | $15.8B | 196.21% | |
| 90 | —TRIPLE-S MGMT CORP | 566,000 | $14.8B | 183.44% | |
| 91 | NTRANATERA INC | 1,576,190 | $14.6B | 181.16% | |
| 92 | AGLEUSDAEGLEA BIOTHERAPEUTICS INC | 1,469,524 | $14.6B | 180.75% | |
| 93 | RCKTROCKET PHARMACEUTICALS INC | 775,000 | $14.5B | 180.17% | |
| 94 | ZLABZAI LAB LTD | 658,160 | $14.1B | 174.23% | |
| 95 | —STEADYMED LTD | 4,246,196 | $13.8B | 171.10% | |
| 96 | —NOVUS THERAPEUTICS INC | 2,537,110 | $12.8B | 158.54% | |
| 97 | AMEDAMEDISYS INC | 207,500 | $12.5B | 155.25% | |
| 98 | —AEGERION PHARMACEUTICALS INC | 15,000,000 | $12.0B | 149.28% | |
| 99 | —WRIGHT MED GROUP N V | 8,746,583 | $12.0B | 148.58% | |
| 100 | BMRNBIOMARIN PHARMACEUTICAL INC | 145,500 | $11.8B | 146.26% |
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