SPRO

Spero Therapeutics, Inc.
$2.58-0.01 (-0.19%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Shares Held

9.190606236234818e+254B

Total Value

$2.1414550441792075e+91T

% of Float

—

Price History

$0.56$1.18$1.80$2.42$3.04Sep 24Jun 25Mar 26

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1GSK plc9,190,606$21.4M2.68%Share
2PFIZER INC2,362,348$5.5M2.33%Share
3VANGUARD GROUP INC1,793,901$4.2M0.00%Share
4Alphabet Inc.889,979$2.1M0.08%Share
5RENAISSANCE TECHNOLOGIES LLC1,279,522$2.0M0.00%Share
6Anson Funds Management LP625,062$1.5M0.14%Share
7GEODE CAPITAL MANAGEMENT, LLC435,744$1.0M0.00%Share
8BlackRock, Inc.432,423$1.0M0.00%Share
9VANGUARD GROUP INC264,115$615K0.00%Share
10Informed Momentum Co LLC218,084$508K0.06%Share
11Ionic Capital Management LLC195,939$456K0.06%Share
12INTREPID FAMILY OFFICE LLC165,000$384K0.33%Share
13ADAR1 Capital Management, LLC113,839$265K0.02%Share
14GROUP ONE TRADING LLC111,800$260K0.00%Call
15UBS Group AG105,078$244K0.00%Share
16Shay Capital LLC60,289$140K0.01%Share
17Capital Asset Advisory Services LLC32,548$81K0.00%Share
18AXXCESS WEALTH MANAGEMENT, LLC32,548$75K0.00%Share
19Three Seasons Wealth, LLC30,000$69K0.01%Share
20VANGUARD GROUP INC25,446$59K0.00%Share
21Invesco Ltd.24,705$57K0.00%Share
22Assenagon Asset Management S.A.18,636$43K0.00%Share
23Torrey Growth & Income Advisors17,025$39K0.01%Share
24UBS Group AG11,369$26K0.00%Share
25Texas Yale Capital Corp.10,000$23K0.00%Share
26FNY Investment Advisers, LLC5,300$12K0.00%Share
27GROUP ONE TRADING LLC1,100$2K0.00%Put
28Tower Research Capital LLC (TRC)7,215$00.00%Share
29TWO SIGMA ADVISERS, LP216,600$00.00%Share
30SUSQUEHANNA INTERNATIONAL GROUP, LLP293,700$00.00%Share
31Quadrature Capital Ltd37,799$00.00%Share
32CITIGROUP INC17$00.00%Share
33CHARLES SCHWAB INVESTMENT MANAGEMENT INC28,565$00.00%Share
34STATE STREET CORP210,151$00.00%Share
35JANE STREET GROUP, LLC64,297$00.00%Share
36JANE STREET GROUP, LLC38,600$00.00%Put
37JANE STREET GROUP, LLC39,513$00.00%Share
38JANE STREET GROUP, LLC54,534$00.00%Share
39DIMENSIONAL FUND ADVISORS LP20,808$00.00%Share
40DIMENSIONAL FUND ADVISORS LP4,957$00.00%Share
41DIMENSIONAL FUND ADVISORS LP4,003$00.00%Share
42GEODE CAPITAL MANAGEMENT, LLC93,451$00.00%Share
43BRIDGEWAY CAPITAL MANAGEMENT, LLC114,800$00.00%Share
44TWO SIGMA INVESTMENTS, LP372,570$00.00%Share
45MILLENNIUM MANAGEMENT LLC24,107$00.00%Share
46CITADEL ADVISORS LLC191,538$00.00%Share
47CITADEL ADVISORS LLC206,326$00.00%Share
48CITADEL ADVISORS LLC73,100$00.00%Put
49BANK OF AMERICA CORP /DE/397$00.00%Share
50BANK OF AMERICA CORP /DE/300$00.00%Share