Casdin Capital, LLC

CIK: 0001534261SEC EDGAR →

Portfolio Value

$1.6B

Holdings

38

As of

Q4 2025

New Positions

5

Closed Positions

6

Top 10 Holdings

RankStockSharesValue% of Portfolio
1

GENEDX HOLDINGS CORP

3,007,164$391.1M
24.29%
2

REVOLUTION MEDICINES INC

2,577,333$205.3M
12.75%
3

BIOLIFE SOLUTIONS INC

5,957,165$144.0M
8.95%
4

STANDARD BIOTOOLS INC

88,783,856$113.6M
7.06%
5

RELAY THERAPEUTICS INC

13,003,574$110.0M
6.83%
6

STRUCTURE THERAPEUTICS INC

1,175,000$81.7M
5.08%
7

ILLUMINA INC

600,000$78.7M
4.89%
8

AVIDITY BIOSCIENCES INC

1,000,000$72.1M
4.48%
9

BEAM THERAPEUTICS INC

1,600,000$44.4M
2.75%
10

GUARDANT HEALTH INC

380,000$38.8M
2.41%

Quarterly Changes

Top Buys

RLAY↑ Increased
$50.8M
GH↑ Increased
$32.6M
ILMN↑ Increased
$28.8M
TXGNEW
$22.8M
DNLI↑ Increased
$17.5M

Top Sells

RVMD↓ Decreased
$81.7M
GPCR↓ Decreased
$38.2M
BLFS↓ Decreased
$27.1M
RNA↓ Decreased
$5.4M
EXASCLOSED
$4.9M

New Positions (7)

$22.8M · 1.4M shares
$11.6M · 175K shares
$11.5M · 260K shares
$11.0M · 40K shares
$8.7M · 50K shares
$8.3M · 1.5M shares
$4.7M · 215K shares

Closed Positions (1)

$4.9M · 90K shares

Sector Breakdown

Sector# HoldingsValue%
Healthcare36$1.5B92.2%
Unknown2$125.3M7.8%