EcoR1 Capital, LLC
CIK: 0001587114SEC EDGAR →
Portfolio Value
$2.2B
Holdings
28
As of
Q4 2025
New Positions
6
Closed Positions
12
Top 10 Holdings
| Rank | Stock | Shares | Value | % of Portfolio |
|---|---|---|---|---|
| 1 | MEREO BIOPHARMA GROUP PLC | 7,856,466 | $3.3B | 148.50% |
| 2 | ZYMEWORKS INC | 22,970,388 | $604.8M | 27.44% |
| 3 | ANAPTYSBIO INC | 7,880,094 | $382.0M | 17.33% |
| 4 | JAZZ PHARMACEUTICALS PLC | 1,706,469 | $290.1M | 13.16% |
| 5 | CRINETICS PHARMACEUTICALS IN | 4,288,120 | $199.6M | 9.06% |
| 6 | CENTESSA PHARMACEUTICALS PLC | 3,115,000 | $77.9M | 3.53% |
| 7 | CRISPR THERAPEUTICS AG | 1,389,276 | $72.9M | 3.31% |
| 8 | MBX BIOSCIENCES INC | 2,123,604 | $67.0M | 3.04% |
| 9 | IMMUNOME INC | 2,855,590 | $61.3M | 2.78% |
| 10 | ORIC PHARMACEUTICALS INC | 6,728,116 | $55.0M | 2.50% |
Quarterly Changes
New Positions (10)
Closed Positions (12)
Sector Breakdown
| Sector | # Holdings | Value | % |
|---|---|---|---|
| Healthcare | 27 | $5.5B | 99.8% |
| Unknown | 1 | $8.6M | 0.2% |