Sofinnova Investments, Inc.

CIK: 0001631134SEC EDGAR →

Portfolio Value

$2.3B

Holdings

60

As of

Q4 2025

New Positions

10

Closed Positions

8

Portfolio Value History

Top 10 Holdings

RankStockSharesValue% of Portfolio
1

NATERA INC

1,550,280$355.2M
15.31%
2

JAZZ PHARMACEUTICALS PLC

959,860$163.2M
7.04%
3

ASTRAZENECA PLC

1,632,334$150.1M
6.47%
4

VERA THERAPEUTICS INC

2,793,987$141.5M
6.10%
5

BRISTOL-MYERS SQUIBB CO

1,512,994$81.6M
3.52%
6

UNITED THERAPEUTICS CORP

157,641$76.8M
3.31%
7

VERTEX PHARMACEUTICALS INC

164,594$74.6M
3.22%
8

ABBVIE INC

317,783$72.6M
3.13%
9

INTUITIVE SURGICAL INC

126,968$71.9M
3.10%
10

COGENT BIOSCIENCES INC

1,973,625$70.1M
3.02%

Quarterly Changes

Top Buys

AZN↑ Increased
$86.8M
JAZZ↑ Increased
$85.6M
BMYNEW
$81.6M
UTHNEW
$76.8M
LLYNEW
$66.3M

Top Sells

GILDCLOSED
$139.0M
UTHCLOSED
$120.6M
BSXCLOSED
$55.6M
QURECLOSED
$54.7M
IBBCLOSED
$46.9M

New Positions (13)

$81.6M · 1.5M shares
$76.8M · 158K shares
$66.3M · 62K shares
$41.4M · 697K shares
$27.6M · 1.1M shares
$26.2M · 333K shares
$6.4M · 527K shares
$6.0M · 46K shares
$4.2M · 177K shares
$2.7M · 60K shares
$2.6M · 153K shares
$1.9M · 83K shares
$1.8M · 23K shares

Closed Positions (12)

$139.0M · 1.3M shares
$120.6M · 288K shares
$55.6M · 569K shares
$54.7M · 937K shares
$46.9M · 325K shares
$40.1M · 400K shares
$22.5M · 474K shares
$18.6M · 900K shares
$15.7M · 167K shares
$11.5M · 187K shares
$5.7M · 250K shares
$1.2M · 31K shares

Sector Breakdown

Sector# HoldingsValue%
Healthcare54$2.1B92.4%
Unknown6$176.9M7.6%