Sofinnova Investments, Inc. Q3 2023 Filing

Filed November 14, 2023

Portfolio Value

$1.6T

Holdings

57

Report Date

Q3 2023

Filing Type

13F-HR

All Holdings (57 positions)

#StockSharesValue% PortfolioType
1
KRTXKaruna Therapeutics Inc
1,381,149$233.5B14.73%
2
NTRANatera Inc
3,100,560$137.2B8.65%
3
AZNAstraZeneca PLC
1,362,836$92.3B5.82%
4
MRKMerck & Co Inc
728,404$75.0B4.73%
5
ASNDAscendis Pharma A/S
754,032$70.6B4.45%
6
RayzeBio Inc
2,419,528$53.7B3.39%
7
DC4Dexcom Inc
550,197$51.3B3.24%
8
AVTEAerovate Therapeutics Inc
3,758,686$51.0B3.22%
9
ISRGIntuitive Surgical Inc
173,277$50.6B3.19%
10
VERAVera Therapeutics Inc
3,467,156$47.5B3.00%
11
CYTKCytokinetics Inc
1,560,164$46.0B2.90%Put
12
ELANElanco Animal Health Inc
3,610,024$40.6B2.56%
13
IWMIShares TR
225,000$39.8B2.51%Put
14
ARGXargenx SE
78,186$38.4B2.42%
15
EX9Exelixis Inc
1,743,364$38.1B2.40%Put
16
IMTXImmatics NV
3,251,509$37.7B2.38%
17
SNYSanofi
695,375$37.3B2.35%
18
KVUEKenvue Inc
1,802,084$36.2B2.28%
19
IDXXIDEXX Laboratories Inc
77,881$34.1B2.15%
20
IMGNEURImmunoGen Inc
2,045,202$32.5B2.05%
21
SNDXSyndax Pharmaceuticals Inc
1,991,817$28.9B1.82%Put
22
IDYAIDEAYA Biosciences Inc
1,037,187$28.0B1.77%
23
ZNTLZentalis Pharmaceuticals Inc
1,211,641$24.3B1.53%
24
SPYSPDR S&P 500 ETF Trust
50,000$21.4B1.35%Put
25
REPLReplimune Group Inc
1,066,944$18.3B1.15%Put
26
INZYInozyme Pharma Inc
4,280,308$18.0B1.13%
27
QQQInvesco QQQ TR
50,000$17.9B1.13%
28
TCE2Celldex Therapeutics Inc
624,259$17.2B1.08%Put
29
AGENEURAgenus Inc
14,964,748$16.9B1.07%Call
30
MLTXMoonLake Immunotherapeutics
292,805$16.7B1.05%
31
Shockwave Med Inc
81,373$16.2B1.02%
32
ALKSAlkermes PLC
537,464$15.1B0.95%
33
INBXUSDInhibrx Inc
743,294$13.6B0.86%
34
YMABUSDY-mAbs Therapeutics Inc
2,194,278$12.0B0.75%
35
MRNS*Marinus Pharmaceuticals Inc
1,306,206$10.5B0.66%Call
36
GPCRStructure Therapeutics Inc
202,119$10.2B0.64%
37
CRSPCRISPR Therapeutics AG
200,000$9.1B0.57%Put
38
GONGeron Corp
3,702,546$7.8B0.50%
39
SRPTSarepta Therapeutics Inc
51,100$6.2B0.39%Call
40
DYNDyne Therapeutics Inc
685,133$6.1B0.39%
41
AXSMAxsome Therapeutics Inc
80,368$5.6B0.35%
42
IMVTImmunovant Inc
139,885$5.4B0.34%
43
NXTCNextcure Inc
2,671,856$3.4B0.22%
44
Nucana PLC
5,599,999$3.4B0.22%
45
BOLT1EURBolt Biotherapeutics Inc
2,754,437$2.9B0.18%
46
Nucana PLC
2,400,000$1.5B0.09%
47
IMTXImmatics NV
318,896$1.1B0.07%
48
SYKStryker Corporation
3,279$896.1M0.06%
49
PDSBPDS Biotechnology Corp
142,635$720.3M0.05%
50
YB4PSavara Inc
157,908$596.9M0.04%
51
GRTXGalera Therapeutics Inc
3,083,712$540.0M0.03%
52
Ikena Oncology Inc
115,712$501.0M0.03%
53
Fusion Pharmaceuticals Inc
117,099$304.5M0.02%
54
MIRMMirum Pharmaceuticals Inc
9,089$287.2M0.02%
55
CBAYUSDCymaBay Therapeutics Inc
11,040$164.6M0.01%Put
56
SPRBSpruce Biosciences Inc
58,029$131.1M0.01%
57
SYBXSynlogic Inc
38,331$107.7M0.01%