Monashee Investment Management LLC

CIK: 0001627608Latest portfolio: $177.5M · Q4 2025

Holdings

40

Total Value

$177.5M

New Positions

28

Closed Positions

47

#StockSharesValue% PortfolioChangeType
1
GPCRSTRUCTURE THERAPEUTICS INC
225,000$15.6M8.82%+25K
2
MDLNMEDLINE INC
300,000$12.6M7.10%NEW
3
SOFISOFI TECHNOLOGIES INC
400,000$10.5M5.90%NEW
4
ULSUL SOLUTIONS INC
130,000$10.3M5.78%NEW
5
IM8NINSMED INC
50,000$8.7M4.90%NEW
6
TERNTERNS PHARMACEUTICALS INC
197,313$8.0M4.49%NEW
7
KYMRKYMERA THERAPEUTICS INC
100,000$7.8M4.38%NEW
8
MIAXMIAMI INTL HLDGS INC
175,000$7.8M4.38%+25K
9
BBIOBRIDGEBIO PHARMA INC
100,000$7.6M4.31%-100,000
10
SLDBSOLID BIOSCIENCES INC
1,349,771$7.6M4.29%NEW
11
LGNLEGENCE CORP
137,940$5.9M3.34%-12,060
12
IMNMIMMUNOME INC
274,861$5.9M3.33%NEW
13
ITTITT INC
32,067$5.6M3.13%NEW
14
CMPXCOMPASS THERAPEUTICS INC
1,000,000$5.4M3.03%-250,000
15
CYTKCYTOKINETICS INC
75,000$4.8M2.69%-25,000
16
WLTHWEALTHFRONT CORP
300,000$4.1M2.30%NEW
17
NKTRNEKTAR THERAPEUTICS
94,134$4.0M2.24%NEW
1875,877$3.8M2.15%NEW
19
ADTADT INC DEL
400,000$3.2M1.82%-50,000
20
EVMNEVOMMUNE INC
183,239$3.1M1.77%NEW
21
GOSSGOSSAMER BIO INC
1,000,000$3.1M1.75%NEW
2255,962$3.1M1.73%NEW
23
LMRILUMEXA IMAGING HOLDINGS INC
150,000$2.8M1.56%NEW
24
ENGNENGENE HOLDINGS INC
295,000$2.7M1.50%NEW
25
AMBQAMBIQ MICRO INC
85,089$2.4M1.37%-114,911

Quarterly Changes

New Positions

Closed Positions

Increased Positions

NameSharesChange
GOSS 5 06/01/271.9M+874K
GPCR225K+25K
MIAX175K+25K
CYTK75K+-25000
AMBQ85K+-114911

Decreased Positions

NameSharesChange
CMPX1.0M-250000
WYFI140K-215000
BBIO100K-100000
ADT400K-50000
FTW198K-26687
LGN138K-12060
BDSX112K12K

Sector Breakdown

Healthcare0.0% ($1.564812600797178e+84T)
Industrials0.0% ($102515936556.3T)
Unknown0.0% ($87023821307.6T)
Financial Services0.0% ($1047.3T)
Technology0.0% ($407.7T)

Filing History

QuarterFiling DatePortfolio ValueHoldings
Q4 2025Feb 12, 2026$177.5M40
Q3 2025Nov 12, 2025$200.5B61
Q2 2025Aug 11, 2025$275.9B57
Q1 2025May 14, 2025$845.1B46
Q4 2024Feb 14, 2025$729.2B38

Fund Information

CIK0001627608
Most Recent FilingFeb 12, 2026
Number of Filings5

Monashee Investment Management LLC is an institutional investment manager that files 13F reports with the SEC. As of the Q4 2025 filing, the fund reported a portfolio valued at $177.5M across 40 holdings. The largest position is STRUCTURE THERAPEUTICS INC (GPCR), representing 8.8% of the portfolio. Compared to the previous quarter, the fund opened 28 new positions and closed 49 positions. 13F filings are required quarterly disclosures that provide transparency into the holdings of institutional investment managers with at least $100 million in qualifying assets.