Opaleye Management Inc. Q4 2024 Filing
Filed February 14, 2025
Portfolio Value
$571.4M
Holdings
39
Report Date
Q4 2024
Filing Type
13F-HR
All Holdings (39 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | HROWHARROW HEALTH INC | 3,990,000 | $133.9M | 23.43% | |
| 2 | TGTXTG THERAPEUTICS INC | 2,260,000 | $68.0M | 11.90% | |
| 3 | CDXSCODEXIS INC | 8,840,000 | $42.2M | 7.38% | |
| 4 | ETONETON PHARMACEUTICALS INC | 2,852,070 | $38.0M | 6.65% | |
| 5 | OCULOCULAR THERAPEUTIX INC | 4,342,500 | $37.1M | 6.49% | |
| 6 | ARVNARVINAS INC | 1,625,000 | $33.6M | 5.89% | |
| 7 | RYTMRHYTHM PHARMACEUTICALS INC | 500,000 | $28.0M | 4.90% | |
| 8 | IMNMIMMUNOME INC | 2,040,000 | $21.7M | 3.79% | |
| 9 | LQDALIQUIDIA CORPORATION | 1,698,142 | $20.0M | 3.49% | |
| 10 | EWTXEDGEWISE THERAPEUTICS INC | 480,000 | $12.8M | 2.24% | |
| 11 | DNAGINKGO BIOWORKS HOLDINGS | 1,200,000 | $11.8M | 2.06% | |
| 12 | CRGXCARGO THERAPEUTICS INC | 750,000 | $10.8M | 1.89% | |
| 13 | TARAPROTARA THERAPEUTICS INC | 1,825,000 | $9.6M | 1.69% | |
| 14 | TRVITREVI THERAPEUTICS INC | 2,317,500 | $9.5M | 1.67% | |
| 15 | JSPRJASPER THERAPEUTICS INC | 400,000 | $8.6M | 1.50% | |
| 16 | NAMSNEWAMSTERDAM PHARMA COMPANY | 325,000 | $8.4M | 1.46% | |
| 17 | SLRNACELYRIN INC | 2,235,000 | $7.2M | 1.26% | |
| 18 | NRIXNURIX THERAPEUTICS INC | 378,500 | $7.1M | 1.25% | |
| 19 | XOMAXOMA CORP DEL | 250,000 | $6.6M | 1.15% | |
| 20 | PCVXVAXCYTE INC | 75,000 | $6.1M | 1.07% | |
| 21 | GOSS 5 06/01/27GOSSAMER BIO INC | 11,500,000 | $6.1M | 1.07% | |
| 22 | ZNTLZENTALIS PHARMACEUTICALS INC | 1,767,500 | $5.4M | 0.94% | |
| 23 | BDSXBIODESIX INC | 3,465,000 | $5.3M | 0.93% | |
| 24 | KPTI 3 10/15/25KARYOPHARM THERAPEUTICS INC | 6,000,000 | $4.7M | 0.82% | |
| 25 | NUVLNUVALENT INC | 58,500 | $4.6M | 0.80% | |
| 26 | GOSSGOSSAMER BIO INC | 4,490,000 | $4.1M | 0.71% | |
| 27 | PTGXPROTAGONIST THERAPEUTICS INC | 105,000 | $4.1M | 0.71% | |
| 28 | EPIEURESSA PHARMA INC | 2,209,998 | $4.0M | 0.69% | |
| 29 | ABCLABCELLERA BIOLOGICS INC | 965,000 | $2.8M | 0.49% | |
| 30 | URGNUROGEN PHARMA LTD | 220,000 | $2.3M | 0.41% | |
| 31 | RZLTREZOLUTE INC | 465,000 | $2.3M | 0.40% | |
| 32 | IMTXIMMATICS NV | 165,000 | $1.2M | 0.21% | |
| 33 | IBIOIBIO INC | 375,000 | $918K | 0.16% | |
| 34 | LXEOLEXEO THERAPEUTICS INC | 130,000 | $855K | 0.15% | |
| 35 | RGNXREGENXBIO Inc | 80,000 | $618K | 0.11% | |
| 36 | VTYXVENTYX BIOSCIENCES | 280,000 | $613K | 0.11% | |
| 37 | PEPGPEPGEN INC | 110,000 | $416K | 0.07% | |
| 38 | STOKSTOKE THERAPEUTICS INC | 25,000 | $275K | 0.05% | |
| 39 | ADGMADAGIO MED HLDGS INC | 110,571 | $116K | 0.02% |