Sofinnova Investments, Inc. Q1 2022 Filing
Filed May 16, 2022
Portfolio Value
$1.3T
Holdings
59
Report Date
Q1 2022
Filing Type
13F-HR
All Holdings (59 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | KRTXKaruna Therapeutics, Inc. | 1,952,441 | $247.6B | 18.79% | |
| 2 | NTRANatera Inc | 3,102,960 | $126.2B | 9.58% | |
| 3 | —Cincor Pharma, Inc. | 5,573,949 | $97.8B | 7.42% | |
| 4 | VERAVera Therapeutics, Inc. | 3,181,442 | $74.7B | 5.67% | |
| 5 | AVTEAerovate Therapeutics, Inc. | 3,758,686 | $68.9B | 5.23% | |
| 6 | NDQInvesco QQQ Trust Series 1 | 175,000 | $63.4B | 4.82% | Put |
| 7 | ASNDAscendis Pharma A/S | 499,824 | $58.7B | 4.45% | |
| 8 | AZNAstraZeneca PLC | 553,903 | $36.7B | 2.79% | |
| 9 | UTHUnited Therapeutics Corp | 199,183 | $35.7B | 2.71% | |
| 10 | IWMiShares Russell 2000 ETF | 150,000 | $30.8B | 2.34% | Put |
| 11 | YMABUSDY-mAbs Therapeutics, Inc | 2,194,278 | $26.1B | 1.98% | |
| 12 | VRTXVertex Pharmaceuticals Inc | 95,003 | $24.8B | 1.88% | |
| 13 | HZNPHorizon Therapeutics PLC | 232,894 | $24.5B | 1.86% | |
| 14 | DC4Dexcom Inc | 40,265 | $20.6B | 1.56% | |
| 15 | RGNXRegenxbio Inc | 614,085 | $20.4B | 1.55% | |
| 16 | ZTSZoetis Inc | 106,574 | $20.1B | 1.53% | |
| 17 | RETAEURReata Pharmaceuticals Inc | 602,545 | $19.7B | 1.50% | |
| 18 | —Sierra Oncology Inc | 572,297 | $18.3B | 1.39% | |
| 19 | XBISpdr S&P Biotech Etf | 200,000 | $18.0B | 1.36% | Put |
| 20 | PTGXProtagonist Therapeutics Inc | 747,441 | $17.7B | 1.34% | Call |
| 21 | OPHTEURIveric Bio Inc | 1,021,211 | $17.2B | 1.30% | |
| 22 | TVTXTravere Therapeutics Inc | 658,249 | $17.0B | 1.29% | |
| 23 | GHGuardant Health Inc | 239,995 | $15.9B | 1.21% | |
| 24 | CCXIEURChemoCentryx Inc | 573,684 | $14.4B | 1.09% | |
| 25 | BMRNBiomarin Pharmaceutical Inc | 176,533 | $13.6B | 1.03% | |
| 26 | NXTCNextcure, Inc | 2,671,856 | $13.0B | 0.99% | |
| 27 | SNDXSyndax Pharmaceuticals Inc | 717,064 | $12.5B | 0.95% | |
| 28 | —Checkmate Pharmaceuticals Inc | 3,606,707 | $11.5B | 0.87% | |
| 29 | INBXUSDInhibrx Inc | 514,640 | $11.5B | 0.87% | |
| 30 | IMTXImmatics NV | 1,268,063 | $10.1B | 0.77% | |
| 31 | JNCEEURJounce Therapeutics Inc | 1,481,219 | $10.1B | 0.76% | |
| 32 | CTIC1USDCTI Biopharma Corp | 1,952,691 | $9.1B | 0.69% | |
| 33 | TORCEURAdicet Bio Inc | 416,289 | $8.3B | 0.63% | |
| 34 | INZYInozyme Pharma, Inc. | 2,028,308 | $8.3B | 0.63% | |
| 35 | BOLT1EURBolt Biotherapeutics, Inc. | 2,754,437 | $7.5B | 0.57% | |
| 36 | —ChemoCentryx Inc | 300,000 | $7.5B | 0.57% | Call |
| 37 | GRTXGalera Therapeutics, Inc | 3,083,712 | $7.3B | 0.56% | |
| 38 | XNCRXencor Inc | 273,992 | $7.3B | 0.55% | |
| 39 | —Akouos, Inc. | 1,515,074 | $7.2B | 0.55% | |
| 40 | BCYCBicycle Therapeutics PLC | 163,559 | $7.2B | 0.54% | |
| 41 | —ObsEva SA | 4,749,623 | $7.2B | 0.54% | |
| 42 | SRPTSarepta Therapeutics Inc | 88,880 | $6.9B | 0.53% | |
| 43 | IMGNEURImmunoGen Inc | 1,428,169 | $6.8B | 0.52% | |
| 44 | —Nucana Plc | 5,599,999 | $5.6B | 0.42% | |
| 45 | FULCFulcrum Therapeutics Inc | 229,509 | $5.4B | 0.41% | |
| 46 | GONGeron Corp | 2,904,762 | $4.0B | 0.30% | Call |
| 47 | PFEPfizer Inc | 49,378 | $2.6B | 0.19% | |
| 48 | —Nucana Plc | 2,400,000 | $2.4B | 0.18% | |
| 49 | CYTKCytokinetics Inc | 62,944 | $2.3B | 0.18% | |
| 50 | ICPTUSDIntercept Pharmaceuticals Inc | 100,000 | $1.6B | 0.12% | Call |
| 51 | —Synlogic Inc. | 574,972 | $1.4B | 0.10% | |
| 52 | AMLXAmylyx Pharmaceuticals Inc | 100,000 | $1.3B | 0.10% | |
| 53 | PDSBPDS Biotechnology Corporation | 142,635 | $883.0M | 0.07% | |
| 54 | —Mink Therapeutics Inc | 331,002 | $745.0M | 0.06% | |
| 55 | —Fusion Pharmaceuticals Inc | 78,066 | $607.0M | 0.05% | |
| 56 | PODDInsulet Corp | 1,066 | $284.0M | 0.02% | |
| 57 | PTCTPTC Therapeutics Inc | 3,480 | $130.0M | 0.01% | |
| 58 | IM8NInsmed Inc | 5,368 | $126.0M | 0.01% | |
| 59 | KRTXKaruna Therapeutics Inc | 636 | $81.0M | 0.01% | |
| 60 | HRTXHeron Therapeutics Inc | 11,060 | $63.0M | 0.00% |