BAKER BROS. ADVISORS LP Q3 2023 Filing
Filed November 14, 2023
Portfolio Value
$17351.0T
Holdings
101
Report Date
Q3 2023
Filing Type
13F-HR
All Holdings (101 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | SGENUSDSeagen Inc. | 44,554,162 | $9452.2T | 54.48% | |
| 2 | ONCBeiGene, Ltd. | 11,668,897 | $2098.9T | 12.10% | |
| 3 | INCYIncyte Corporation | 36,178,566 | $2090.0T | 12.05% | |
| 4 | ACADACADIA Pharmaceuticals Inc. | 42,864,612 | $893.3T | 5.15% | |
| 5 | BMRNBioMarin Pharmaceutical Inc. | 3,810,248 | $337.1T | 1.94% | |
| 6 | MDGLMadrigal Pharmaceuticals, Inc. | 1,545,113 | $225.6T | 1.30% | |
| 7 | RYTMRhythm Pharmaceuticals, Inc. | 6,702,349 | $153.7T | 0.89% | |
| 8 | ROIVRoivant Sciences Ltd. | 11,877,171 | $138.7T | 0.80% | |
| 9 | IMCRImmunocore Holdings plc | 2,520,731 | $130.8T | 0.75% | |
| 10 | —Invitae Corporation | 300,000,000 | $130.4T | 0.75% | |
| 11 | AKROAkero Therapeutics, Inc. | 2,368,378 | $119.8T | 0.69% | |
| 12 | ABCLAbCellera Biologics Inc. | 20,763,323 | $95.5T | 0.55% | |
| 13 | BCRXBioCryst Pharmaceuticals, Inc. | 12,710,818 | $90.0T | 0.52% | |
| 14 | REPLReplimune Group, Inc. | 4,578,280 | $78.3T | 0.45% | |
| 15 | TRDAEntrada Therapeutics, Inc. | 4,865,819 | $76.9T | 0.44% | |
| 16 | RVMDRevolution Medicines, Inc. | 2,691,493 | $74.5T | 0.43% | |
| 17 | ARGXargenx SE | 151,215 | $74.3T | 0.43% | |
| 18 | SWTXSpringWorks Therapeutics, Inc. | 2,999,846 | $69.4T | 0.40% | |
| 19 | KYMRKymera Therapeutics, Inc. | 4,750,400 | $66.0T | 0.38% | |
| 20 | IMTXImmatics N.V. | 5,640,816 | $65.3T | 0.38% | |
| 21 | MRTXEURMirati Therapeutics, Inc. | 1,409,784 | $61.4T | 0.35% | |
| 22 | KNSAKiniksa Pharmaceuticals, Ltd. | 2,809,577 | $48.8T | 0.28% | |
| 23 | RAREUltragenyx Pharmaceutical Inc. | 1,366,547 | $48.7T | 0.28% | |
| 24 | DNLIDenali Therapeutics Inc. | 2,292,003 | $47.3T | 0.27% | |
| 25 | PRLDPrelude Therapeutics Inc. | 10,123,824 | $31.3T | 0.18% | |
| 26 | KODKodiak Sciences Inc. | 17,310,490 | $31.2T | 0.18% | |
| 27 | NRIXNurix Therapeutics, Inc. | 3,882,125 | $30.5T | 0.18% | |
| 28 | BMEABiomea Fusion, Inc. | 2,108,949 | $29.0T | 0.17% | |
| 29 | IDYAIDEAYA Biosciences, Inc. | 1,062,123 | $28.7T | 0.17% | |
| 30 | CERSCerus Corporation | 17,239,501 | $27.9T | 0.16% | |
| 31 | AVTEAerovate Therapeutics, Inc. | 1,963,479 | $26.6T | 0.15% | |
| 32 | 1K0IGM Biosciences, Inc. | 3,157,764 | $26.4T | 0.15% | |
| 33 | XENEXenon Pharmaceuticals Inc. | 751,639 | $25.7T | 0.15% | |
| 34 | CABACabaletta Bio, Inc. | 1,594,000 | $24.3T | 0.14% | |
| 35 | GLUEMonte Rosa Therapeutics, Inc. | 4,916,095 | $23.5T | 0.14% | |
| 36 | —DBV Technologies S.A. | 14,614,264 | $19.9T | 0.11% | |
| 37 | KRYSKrystal Biotech, Inc. | 169,934 | $19.7T | 0.11% | |
| 38 | VERVVerve Therapeutics, Inc. | 1,416,530 | $18.8T | 0.11% | |
| 39 | BCYCBicycle Therapeutics plc | 843,814 | $17.0T | 0.10% | |
| 40 | IMVTImmunovant, Inc. | 425,009 | $16.3T | 0.09% | |
| 41 | COGTCogent Biosciences, Inc. | 1,292,966 | $12.6T | 0.07% | |
| 42 | DAWNDay One Biopharmaceuticals, Inc. | 1,000,000 | $12.3T | 0.07% | |
| 43 | PRMEPrime Medicine, Inc. | 1,028,466 | $9.8T | 0.06% | |
| 44 | TSVT*2seventy bio, Inc. | 2,497,526 | $9.8T | 0.06% | |
| 45 | RLAYRelay Therapeutics, Inc. | 1,160,117 | $9.8T | 0.06% | |
| 46 | PACBPacific Biosciences of California, Inc. | 1,127,782 | $9.4T | 0.05% | |
| 47 | IM8NInsmed Incorporated | 343,000 | $8.7T | 0.05% | |
| 48 | ADAPYAdaptimmune Therapeutics plc | 10,969,282 | $8.6T | 0.05% | |
| 49 | TNGXTango Therapeutics, Inc. | 750,000 | $8.4T | 0.05% | |
| 50 | HRTXHeron Therapeutics, Inc. | 8,131,678 | $8.4T | 0.05% | |
| 51 | ARVNArvinas, Inc. | 413,481 | $8.1T | 0.05% | |
| 52 | TSHATaysha Gene Therapies, Inc. | 2,504,756 | $7.9T | 0.05% | |
| 53 | SANASana Biotechnology, Inc. | 2,000,000 | $7.7T | 0.04% | |
| 54 | —bluebird bio, Inc. | 2,499,715 | $7.6T | 0.04% | |
| 55 | SPRYARS Pharmaceuticals, Inc. | 2,006,451 | $7.6T | 0.04% | |
| 56 | SGMTSagimet Biosciences Inc. | 815,359 | $7.2T | 0.04% | |
| 57 | TCRXTScan Therapeutics, Inc. | 2,784,792 | $7.1T | 0.04% | |
| 58 | GONGeron Corporation | 3,061,224 | $6.5T | 0.04% | |
| 59 | —Athira Pharma, Inc. | 3,153,807 | $6.4T | 0.04% | |
| 60 | ALECAlector, Inc. | 964,851 | $6.3T | 0.04% | |
| 61 | —Invitae Corporation | 9,274,000 | $6.2T | 0.04% | |
| 62 | MIRMMirum Pharmaceuticals, Inc. | 190,476 | $6.0T | 0.03% | |
| 63 | EWTXEdgewise Therapeutics, Inc. | 1,049,699 | $6.0T | 0.03% | |
| 64 | SMMTSummit Therapeutics Inc. | 3,140,473 | $5.9T | 0.03% | |
| 65 | STOKStoke Therapeutics, Inc. | 1,485,915 | $5.9T | 0.03% | |
| 66 | HOOKGBPHOOKIPA Pharma Inc. | 8,065,398 | $5.0T | 0.03% | |
| 67 | MORFMorphic Holding, Inc. | 215,800 | $4.9T | 0.03% | |
| 68 | CELCCelcuity Inc. | 535,478 | $4.9T | 0.03% | |
| 69 | —Neoleukin Therapeutics, Inc. | 1,221,414 | $4.8T | 0.03% | |
| 70 | WHWKAadi Bioscience, Inc. | 989,928 | $4.8T | 0.03% | |
| 71 | OPTEYOpthea Limited | 2,690,891 | $4.7T | 0.03% | |
| 72 | NTRANatera, Inc. | 100,000 | $4.4T | 0.03% | |
| 73 | DSGNDesign Therapeutics, Inc. | 1,500,000 | $3.5T | 0.02% | |
| 74 | PRAXPraxis Precision Medicines, Inc. | 1,879,915 | $3.2T | 0.02% | |
| 75 | CMPXCompass Therapeutics, Inc. | 1,557,630 | $3.1T | 0.02% | |
| 76 | TLISTalis Biomedical Corporation | 508,323 | $2.9T | 0.02% | |
| 77 | GRCLGracell Biotechnologies Inc. | 1,000,000 | $2.9T | 0.02% | |
| 78 | SERASera Prognostics, Inc. | 1,515,342 | $2.8T | 0.02% | |
| 79 | PCVXVaxcyte, Inc. | 48,885 | $2.5T | 0.01% | |
| 80 | XNCRXencor, Inc. | 123,127 | $2.5T | 0.01% | |
| 81 | KALAKALA BIO, Inc. | 266,613 | $2.4T | 0.01% | |
| 82 | 698Achilles Therapeutics plc | 2,557,149 | $2.3T | 0.01% | |
| 83 | IPSCCentury Therapeutics, Inc. | 1,149,340 | $2.3T | 0.01% | |
| 84 | —Affimed N.V. | 4,448,644 | $2.1T | 0.01% | |
| 85 | ISREURPerspective Therapeutics, Inc. | 7,639,703 | $2.1T | 0.01% | |
| 86 | TILInstil Bio, Inc. | 4,704,395 | $2.0T | 0.01% | |
| 87 | PMVPPMV Pharmaceuticals, Inc. | 322,024 | $2.0T | 0.01% | |
| 88 | ANABAnaptysBio, Inc. | 106,197 | $1.9T | 0.01% | |
| 89 | —POINT Biopharma Global Inc. | 249,968 | $1.7T | 0.01% | |
| 90 | 5E7iTeos Therapeutics, Inc. | 150,346 | $1.6T | 0.01% | |
| 91 | CYPHLeap Therapeutics, Inc. | 1,172,175 | $1.6T | 0.01% | |
| 92 | ALGSAligos Therapeutics, Inc. | 2,076,400 | $1.6T | 0.01% | |
| 93 | —Mersana Therapeutics, Inc. | 1,086,115 | $1.4T | 0.01% | |
| 94 | VORVor Biopharma Inc. | 633,848 | $1.3T | 0.01% | |
| 95 | NVTA1EURInvitae Corporation | 1,764,546 | $1.1T | 0.01% | |
| 96 | RNAAvidity Biosciences, Inc. | 166,347 | $1.1T | 0.01% | |
| 97 | BCELAtreca, Inc. | 3,532,760 | $922.0B | 0.01% | |
| 98 | —Genetron Holdings Limited | 455,306 | $369.8B | 0.00% | |
| 99 | TARAProtara Therapeutics, Inc. | 199,671 | $333.5B | 0.00% | |
| 100 | FHTXFoghorn Therapeutics Inc. | 45,027 | $225.1B | 0.00% |
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