Rock Springs Capital Management LP Q4 2023 Filing

Filed February 14, 2024

Portfolio Value

$4.1B

Holdings

104

Report Date

Q4 2023

Filing Type

13F-HR

All Holdings (104 positions)

#	Stock	Shares	Value	% Portfolio	Type
1	GOSS 5 06/01/27GOSSAMER BIO INC	9,573,000	$3.0B	73.85%
2	ADAPYADAPTIMMUNE THERAPEUTICS PLC	2,425,468	$1.0B	24.62%
3	2L9BLUEPRINT MEDICINES CORP	2,881,567	$265.0M	6.52%
4	IMCRIMMUNOCORE HLDGS PLC	2,661,507	$181.0M	4.46%
5	KRTXKARUNA THERAPEUTICS INC	515,024	$163.0M	4.01%
6	NBIXNEUROCRINE BIOSCIENCES INC	1,196,000	$157.0M	3.86%
7	HUMHUMANA INC	310,000	$141.0M	3.47%
8	PENPENUMBRA INC	537,500	$135.0M	3.32%
9	EVHEVOLENT HEALTH INC	3,960,000	$130.0M	3.20%
10	CERE1EURCEREVEL THERAPEUTICS HLDNG I	2,674,245	$113.0M	2.78%
11	AGLAGILON HEALTH INC	8,630,000	$108.0M	2.66%
12	ISRGINTUITIVE SURGICAL INC	298,500	$100.0M	2.46%
13	PODDINSULET CORP	431,750	$93.0M	2.29%
14	ARGXARGENX SE	229,250	$87.0M	2.14%
15	ACHCACADIA HEALTHCARE COMPANY IN	1,073,500	$83.0M	2.04%
16	RAREULTRAGENYX PHARMACEUTICAL IN	1,754,038	$83.0M	2.04%
17	EXASEXACT SCIENCES CORP	1,019,500	$75.0M	1.85%
18	DC4DEXCOM INC	596,000	$73.0M	1.80%
19	BSXBOSTON SCIENTIFIC CORP	1,232,500	$71.0M	1.75%
20	RYTMRHYTHM PHARMACEUTICALS INC	1,522,893	$70.0M	1.72%
21	AFWALIGN TECHNOLOGY INC	220,000	$60.0M	1.48%
22	FRPTFRESHPET INC	662,500	$57.0M	1.40%
23	XENEXENON PHARMACEUTICALS INC	1,255,577	$57.0M	1.40%
24	MIRMMIRUM PHARMACEUTICALS INC	1,851,464	$54.0M	1.33%
25	PHRPHREESIA INC	2,206,700	$51.0M	1.26%
26	MRTXEURMIRATI THERAPEUTICS INC	835,776	$49.0M	1.21%
27	EWEDWARDS LIFESCIENCES CORP	647,300	$49.0M	1.21%
28	WSTWEST PHARMACEUTICAL SVSC INC	137,250	$48.0M	1.18%
29	AGIOAGIOS PHARMACEUTICALS INC	2,152,173	$47.0M	1.16%
30	MDGLMADRIGAL PHARMACEUTICALS INC	198,169	$45.0M	1.11%
31	ALNYALNYLAM PHARMACEUTICALS INC	235,000	$44.0M	1.08%
32	—OLINK HLDG AB	1,676,500	$42.0M	1.03%
33	IMVTIMMUNOVANT INC	983,301	$41.0M	1.01%
34	ACCDEURACCOLADE INC	3,485,000	$41.0M	1.01%
35	KYMRKYMERA THERAPEUTICS INC	1,522,238	$38.0M	0.94%
36	TCE2CELLDEX THERAPEUTICS INC NEW	969,646	$38.0M	0.94%
37	IRTCIRHYTHM TECHNOLOGIES INC	350,750	$37.0M	0.91%
38	ASNDASCENDIS PHARMA A/S	290,000	$36.0M	0.89%
39	PCRXPACIRA BIOSCIENCES INC	1,055,500	$35.0M	0.86%
40	LFSTLIFESTANCE HEALTH GROUP INC	4,535,000	$35.0M	0.86%
41	AZTAAZENTA INC	507,500	$33.0M	0.81%
42	SRPTSAREPTA THERAPEUTICS INC	327,600	$31.0M	0.76%
43	ZLABZAI LAB LTD	1,137,023	$31.0M	0.76%
44	LEGNLEGEND BIOTECH CORP	492,444	$29.0M	0.71%
45	WRBYWARBY PARKER INC	2,028,300	$28.0M	0.69%
46	AKROAKERO THERAPEUTICS INC	1,081,064	$25.0M	0.62%
47	TVTXTRAVERE THERAPEUTICS INC	2,771,446	$24.0M	0.59%
48	DVAXDYNAVAX TECHNOLOGIES CORP	1,675,474	$23.0M	0.57%
49	MRUSMERUS N V	872,069	$23.0M	0.57%
50	IMGNEURIMMUNOGEN INC	759,365	$22.0M	0.54%
51	PRTAPROTHENA CORP PLC	625,048	$22.0M	0.54%
52	SWAVUSDSHOCKWAVE MED INC	120,000	$22.0M	0.54%
53	NVROEURNEVRO CORP	1,025,000	$22.0M	0.54%
54	AMGNAMGEN INC	74,500	$21.0M	0.52%
55	INSPINSPIRE MED SYS INC	99,000	$20.0M	0.49%
56	IRONDISC MEDICINE INC	363,468	$20.0M	0.49%
57	RVMDREVOLUTION MEDICINES INC	725,152	$20.0M	0.49%
58	BCRXBIOCRYST PHARMACEUTICALS INC	3,270,381	$19.0M	0.47%
59	IMTXIMMATICS N.V	1,875,466	$19.0M	0.47%
60	MREOMEREO BIOPHARMA GROUP PLC	7,983,851	$18.0M	0.44%
61	COLLCOLLEGIUM PHARMACEUTICAL INC	562,000	$17.0M	0.42%
62	INZYINOZYME PHARMA INC	3,681,174	$15.0M	0.37%
63	AM6AMICUS THERAPEUTICS INC	1,063,806	$15.0M	0.37%
64	BMRNBIOMARIN PHARMACEUTICAL INC	148,832	$14.0M	0.34%
65	—ICOSAVAX INC	868,409	$13.0M	0.32%
66	KRYSKRYSTAL BIOTECH INC	103,969	$12.0M	0.30%
67	MGNXMACROGENICS INC	1,178,796	$11.0M	0.27%
68	INBXUSDINHIBRX INC	301,400	$11.0M	0.27%	Call
69	GPCRSTRUCTURE THERAPEUTICS INC	286,676	$11.0M	0.27%
70	MLYSMINERALYS THERAPEUTICS INC	1,167,492	$10.0M	0.25%
71	NUVB/WSNUVATION BIO INC	134,028	$8.0M	0.20%
72	LUNGPULMONX CORP	652,400	$8.0M	0.20%
73	ABOSACUMEN PHARMACEUTICALS INC	2,300,059	$8.0M	0.20%
74	CMPXCOMPASS THERAPEUTICS INC	5,513,788	$8.0M	0.20%
75	RLAYRELAY THERAPEUTICS INC	673,966	$7.0M	0.17%
76	SPRBSPRUCE BIOSCIENCES INC	2,609,125	$7.0M	0.17%
77	AMLXAMYLYX PHARMACEUTICALS INC	535,012	$7.0M	0.17%
78	—MERSANA THERAPEUTICS INC	3,046,782	$7.0M	0.17%
79	EDAEDAP TMS S A	1,386,425	$7.0M	0.17%
80	OSCROSCAR HEALTH INC	735,000	$6.0M	0.15%
81	PLRXPLIANT THERAPEUTICS INC	384,996	$6.0M	0.15%
82	EPIEURESSA PHARMA INC	677,005	$4.0M	0.10%
83	FULCFULCRUM THERAPEUTICS INC	727,673	$4.0M	0.10%
84	SGMTSAGIMET BIOSCIENCES INC	738,355	$4.0M	0.10%
85	ACRSACLARIS THERAPEUTICS INC	2,998,495	$3.0M	0.07%
86	AUPHAURINIA PHARMACEUTICALS INC	412,570	$3.0M	0.07%
87	CYPHLEAP THERAPEUTICS INC	832,937	$3.0M	0.07%
88	BEAMBEAM THERAPEUTICS INC	111,430	$3.0M	0.07%
89	APLTAPPLIED THERAPEUTICS INC	895,195	$2.0M	0.05%
90	TVTX 2.5 09/15/25TRAVERE THERAPEUTICS INC	3,250,000	$2.0M	0.05%
91	CGENCOMPUGEN LTD	1,289,990	$2.0M	0.05%
92	BMEABIOMEA FUSION INC	181,147	$2.0M	0.05%
93	GOSSGOSSAMER BIO INC	3,266,960	$2.0M	0.05%
94	NVV1NOVAVAX INC	537,625	$2.0M	0.05%
95	OKURRENEO PHARMACEUTICALS INC	751,730	$1.0M	0.02%
96	VINCVINCERX PHARMA INC	891,719	$1.0M	0.02%
97	NBIX 2.25 05/15/24NEUROCRINE BIOSCIENCES INC	1,000,000	$1.0M	0.02%
98	VIGLVIGIL NEUROSCIENCE INC	471,958	$1.0M	0.02%
99	XLOXILIO THERAPEUTICS INC	1,440,759	$792K	0.02%
100	NVRO 2.75 04/01/25NEVRO CORP	500,000	$482K	0.01%

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