RA CAPITAL MANAGEMENT, L.P. Q4 2024 Filing
Filed February 14, 2025
Portfolio Value
$7.5T
Holdings
89
Report Date
Q4 2024
Filing Type
13F-HR
All Holdings (89 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | ASNDASCENDIS PHARMA A/S - ADR | 10,112,744 | $1.4T | 18.53% | |
| 2 | PCVXVAXCYTE INC | 8,689,190 | $711.3B | 9.47% | |
| 3 | JANXJANUX THERAPEUTICS INC | 10,365,652 | $555.0B | 7.39% | |
| 4 | RYTMRHYTHM PHARMACEUTICALS INC | 6,084,412 | $340.6B | 4.53% | |
| 5 | LEGNLEGEND BIOTECH CORP-ADR | 7,506,934 | $244.3B | 3.25% | |
| 6 | EWTXEDGEWISE THERAPEUTICS INC | 8,909,091 | $237.9B | 3.17% | |
| 7 | NAMSNEWAMSTERDAM PHARMA CO NV | 8,845,000 | $227.3B | 3.03% | |
| 8 | WVEWAVE LIFE SCIENCES LTD | 18,202,009 | $225.2B | 3.00% | |
| 9 | ACLXARCELLX INC | 2,787,327 | $213.8B | 2.84% | |
| 10 | RNAAVIDITY BIOSCIENCES INC | 6,300,408 | $183.2B | 2.44% | |
| 11 | SEPNSEPTERNA INC | 6,995,858 | $160.2B | 2.13% | |
| 12 | DYNDYNE THERAPEUTICS INC | 6,381,144 | $150.3B | 2.00% | |
| 13 | TYRATYRA BIOSCIENCES INC | 10,637,290 | $147.9B | 1.97% | |
| 14 | RXSTRXSIGHT INC | 3,743,018 | $128.7B | 1.71% | |
| 15 | BCAXBICARA THERAPEUTICS INC | 6,955,993 | $121.2B | 1.61% | |
| 16 | LENZLENZ THERAPEUTICS INC | 4,178,823 | $120.6B | 1.61% | |
| 17 | SPRYARS PHARMACEUTICALS INC | 10,860,977 | $114.6B | 1.52% | |
| 18 | ETNBGBP89BIO INC | 14,175,398 | $110.9B | 1.48% | |
| 19 | XBISPDR S&P BIOTECH ETF | 1,228,240 | $110.6B | 1.47% | |
| 20 | GONGERON CORP | 30,009,536 | $106.2B | 1.41% | |
| 21 | ARTVARTIVA BIOTHERAPEUTICS INC | 9,853,302 | $99.3B | 1.32% | |
| 22 | AXSMAXSOME THERAPEUTICS INC | 1,000,000 | $84.6B | 1.13% | |
| 23 | VRNAVERONA PHARMA PLC - ADR | 1,766,830 | $82.1B | 1.09% | |
| 24 | DAWNDAY ONE BIOPHARMACEUTICALS I | 5,755,577 | $72.9B | 0.97% | |
| 25 | APGEAPOGEE THERAPEUTICS INC | 1,569,491 | $71.1B | 0.95% | |
| 26 | MLYSMINERALYS THERAPEUTICS INC | 4,850,984 | $59.7B | 0.79% | |
| 27 | PRAXPRAXIS PRECISION MEDICINES I | 761,955 | $58.6B | 0.78% | |
| 28 | CLYMCLIMB BIO INC | 31,419,267 | $56.6B | 0.75% | |
| 29 | RXRXRECURSION PHARMACEUTICALS-A | 7,725,096 | $52.2B | 0.69% | |
| 30 | TRMLTOURMALINE BIO INC | 2,538,925 | $51.5B | 0.69% | |
| 31 | ACRVACRIVON THERAPEUTICS INC | 8,340,508 | $50.2B | 0.67% | |
| 32 | FULCFULCRUM THERAPEUTICS INC | 10,229,099 | $48.1B | 0.64% | |
| 33 | TXG10X GENOMICS INC-CLASS A | 3,279,401 | $47.1B | 0.63% | |
| 34 | GHRSGH RESEARCH PLC | 6,686,689 | $46.8B | 0.62% | |
| 35 | CATBUSDASTRIA THERAPEUTICS INC | 5,105,213 | $45.6B | 0.61% | |
| 36 | VORVOR BIOPHARMA INC | 39,646,039 | $44.0B | 0.59% | |
| 37 | GPCRSTRUCTURE THERAPEUTICS INC | 1,517,418 | $41.2B | 0.55% | |
| 38 | DNTHDIANTHUS THERAPEUTICS INC | 1,866,400 | $40.7B | 0.54% | |
| 39 | PEPGPEPGEN INC | 10,689,545 | $40.5B | 0.54% | |
| 40 | EVHEVOLENT HEALTH INC - A | 3,577,197 | $40.2B | 0.54% | |
| 41 | KURAKURA ONCOLOGY INC | 4,451,041 | $38.8B | 0.52% | |
| 42 | IDYAIDEAYA BIOSCIENCES INC | 1,347,252 | $34.6B | 0.46% | |
| 43 | ZLABZAI LAB LTD-ADR | 1,295,040 | $33.9B | 0.45% | |
| 44 | CMRXEURCHIMERIX INC | 8,800,000 | $30.6B | 0.41% | |
| 45 | CDTXCIDARA THERAPEUTICS INC | 1,092,796 | $29.4B | 0.39% | |
| 46 | MBXMBX BIOSCIENCES INC | 1,511,334 | $27.9B | 0.37% | |
| 47 | NKTXNKARTA INC | 10,805,129 | $26.9B | 0.36% | |
| 48 | ABOSACUMEN PHARMACEUTICALS INC | 14,932,063 | $25.7B | 0.34% | |
| 49 | FDMT4D MOLECULAR THERAPEUTICS IN | 4,563,211 | $25.4B | 0.34% | |
| 50 | NRIXNURIX THERAPEUTICS INC | 1,333,333 | $25.1B | 0.33% | |
| 51 | SERASERA PROGNOSTICS INC-A | 3,032,808 | $24.7B | 0.33% | |
| 52 | AVTEAEROVATE THERAPEUTICS INC | 9,192,092 | $24.4B | 0.32% | |
| 53 | EYPTEYEPOINT PHARMACEUTICALS INC | 3,181,818 | $23.7B | 0.32% | |
| 54 | LRMRLARIMAR THERAPEUTICS INC | 6,045,351 | $23.4B | 0.31% | |
| 55 | CBLLCERIBELL INC | 824,582 | $21.3B | 0.28% | |
| 56 | TVTXTRAVERE THERAPEUTICS INC | 1,150,000 | $20.0B | 0.27% | |
| 57 | ELVNENLIVEN THERAPEUTICS INC | 848,986 | $19.1B | 0.25% | |
| 58 | TSHATAYSHA GENE THERAPIES INC | 10,872,503 | $18.8B | 0.25% | |
| 59 | ALECALECTOR INC | 9,695,228 | $18.3B | 0.24% | |
| 60 | TARAPROTARA THERAPEUTIC INC | 3,400,000 | $18.0B | 0.24% | |
| 61 | CCCCC4 THERAPEUTICS INC | 4,878,000 | $17.6B | 0.23% | |
| 62 | SLDBSOLID BIOSCIENCES INC | 4,330,446 | $17.3B | 0.23% | |
| 63 | PLRXPLIANT THERAPEUTICS INC | 1,281,000 | $16.9B | 0.22% | |
| 64 | DRUGBright Minds Biosciences Inc | 460,829 | $16.6B | 0.22% | |
| 65 | 5E7ITEOS THERAPEUTICS INC | 2,092,259 | $16.1B | 0.21% | |
| 66 | BCYCBICYCLE THERAPEUTICS PLC-ADR | 1,093,477 | $15.3B | 0.20% | |
| 67 | ELDNELEDON PHARMACEUTICALS INC | 3,566,338 | $14.7B | 0.20% | |
| 68 | IM8NINSMED INC | 200,000 | $13.8B | 0.18% | |
| 69 | XNCRXENCOR INC | 575,000 | $13.2B | 0.18% | |
| 70 | IMTXIMMATICS NV | 1,750,000 | $12.4B | 0.17% | |
| 71 | ACRSACLARIS THERAPEUTICS INC | 4,666,667 | $11.6B | 0.15% | |
| 72 | MNPRMONOPAR THERAPEUTICS INC | 511,207 | $11.2B | 0.15% | |
| 73 | THRDTHIRD HARMONIC BIO INC | 960,620 | $9.9B | 0.13% | |
| 74 | HOWLWEREWOLF THERAPEUTICS INC | 6,144,881 | $9.1B | 0.12% | |
| 75 | ARVNARVINAS INC | 421,348 | $8.1B | 0.11% | |
| 76 | ZURAZURA BIO LTD | 3,217,503 | $8.0B | 0.11% | |
| 77 | —PERCEPTIVE CAPITAL SOLUTIONS | 750,000 | $7.6B | 0.10% | |
| 78 | BIOABIOAGE LABS INC | 1,310,589 | $7.6B | 0.10% | |
| 79 | TORCEURADICET BIO INC | 7,541,000 | $7.3B | 0.10% | |
| 80 | AVTXAVALO THERAPEUTICS INC | 967,000 | $7.2B | 0.10% | |
| 81 | BOLDBOUNDLESS BIO INC | 2,180,631 | $6.3B | 0.08% | |
| 82 | ENTAENANTA PHARMACEUTICALS INC | 1,038,000 | $6.0B | 0.08% | |
| 83 | NAMSNEWAMSTERDAM PHARMA CO NV-27 | 333,333 | $4.7B | 0.06% | |
| 84 | SRZNSURROZEN INC | 282,580 | $4.1B | 0.05% | |
| 85 | LXEOLEXEO THERAPEUTICS INC | 546,554 | $3.6B | 0.05% | |
| 86 | ALLKGUSDALLAKOS INC | 1,129,931 | $1.4B | 0.02% | |
| 87 | SRRKSCHOLAR ROCK HOLDING CORP | 17,616 | $761.4M | 0.01% | |
| 88 | RGLSREGULUS THERAPEUTICS INC | 336,843 | $532.2M | 0.01% | |
| 89 | SCLXUSDSCILEX HOLDING CO | 1,036,218 | $441.8M | 0.01% |