Siren, L.L.C. Q1 2025 Filing
Filed May 14, 2025
Portfolio Value
$1.8B
Holdings
116
Report Date
Q1 2025
Filing Type
13F-HR
All Holdings (116 positions)
| Stock | Value |
|---|---|
SRRKScholar Rock Holding Corp | $297.4M |
ONCBeigene Ltd | $135.7M |
KYMRKymera Therapeutics Inc | $88.7M |
2L9Blueprint Medicines Corp | $64.3M |
CRNXCrinetics Pharmaceuticals Inc | $56.6M |
APLSApellis Pharmaceuticals Inc | $56.4M |
IRONDisc Medicine Inc | $53.2M |
SLNOSoleno Therapeutics Inc | $52.0M |
ASNDAscendis Pharma A/S | $44.8M |
MRUSMerus NV | $43.9M |
BCAXBicara Therapeutics Inc | $42.6M |
CNTACentessa Pharmaceuticals PLC | $42.6M |
NAMSNewAmsterdam Pharma Company NV | $39.1M |
EWTXEdgewise Therapeutics Inc | $37.3M |
ARWRArrowhead Pharmaceuticals Inc | $34.0M |
RNAAvidity Biosciences Inc | $32.8M |
WVEWAVE Life Sciences Ltd | $29.9M |
TBLATaboola.com Ltd | $29.4M |
DYNDyne Therapeutics Inc | $28.4M |
SLDBSolid Biosciences Inc | $27.4M |
XENEXenon Pharmaceuticals Inc | $24.6M |
APGEApogee Therapeutics Inc | $22.2M |
RVMDRevolution Medicines Inc | $19.9M |
TRVITrevi Therapeutics Inc | $18.0M |
VERAVera Therapeutics Inc | $17.9M |
PRTAProthena Corporation PLC | $15.9M |
BCYCBicycle Therapeutics PLC | $15.4M |
STOKStoke Therapeutics Inc | $14.9M |
RYTMRhythm Pharmaceuticals Inc | $14.7M |
SMMTSummit Therapeutics Inc | $13.4M |
SEPNSepterna Inc | $12.8M |
RCUSArcus Biosciences Inc | $12.7M |
IHSIHS Holding Limited | $12.3M |
ERASErasca Inc | $12.0M |
DNLIDenali Therapeutics Inc | $11.2M |
PCVXVaxcyte Inc | $11.2M |
AMZNAmazon.com Inc | $10.7M |
MSFTMicrosoft Corp | $10.7M |
RELYRemitly Global Inc | $10.2M |
TSHATaysha Gene Therapies Inc | $9.1M |
CGEMCullinan Therapeutics Inc | $9.0M |
CRWDCrowdStrike Holdings Inc | $8.8M |
SLNSilence Therapeutics PLC | $7.9M |
GOOGLAlphabet Inc | $7.8M |
RNACCartesian Therapeutics Inc | $7.4M |
ADBEAdobe Inc | $7.4M |
KRROKorro Bio Inc | $7.3M |
NOWServiceNow Inc | $7.3M |
SEERSeer Inc | $6.8M |
PDDPDD Holdings Inc | $6.3M |
SYRESpyre Therapeutics Inc | $5.9M |
GOSSGossamer Bio Inc | $5.7M |
ORICOric Pharmaceuticals Inc | $5.6M |
UPBUpstream Bio Inc | $4.8M |
NVDANVIDIA Corp | $4.8M |
TSMTaiwan Semiconductor Manufacturing Co Ltd | $4.7M |
DDOGDatadog Inc | $4.7M |
NMRANeumora Therapeutics Inc | $4.4M |
FROGJfrog Ltd | $4.2M |
DTDynatrace Inc | $4.1M |
MTSRMetsera Inc | $4.1M |
RCKTRocket Pharmaceuticals Inc | $3.9M |
CRMSalesforce Inc | $3.9M |
N1UANew Oriental Education & Technology Group Inc | $3.8M |
RAPPRapport Therapeutics Inc | $3.8M |
IONQIONQ Inc | $3.8M |
1K0IGM Biosciences Inc | $3.7M |
WHWKWhitehawk Therapeutics Inc | $3.7M |
TILInstil Bio Inc | $3.5M |
TNGXTango Therapeutics Inc | $3.5M |
VIGLVigil Neuroscience Inc | $3.5M |
SIONSionna Therapeutics Inc | $3.4M |
NBISNebius Group NV | $3.0M |
FHTXFoghorn Therapeutics Inc. | $2.6M |
RDDTReddit Inc | $2.5M |
LPLALPL Financial Holdings Inc | $2.5M |
SGMTSagimet Biosciences Inc | $2.4M |
ELDNEledon Pharmaceuticals Inc | $2.3M |
TSLATesla Inc | $2.3M |
KLRSKalaris Therapeutics Inc | $2.3M |
MRVLMarvell Technology Inc | $2.3M |
QCOMQualcomm Inc | $2.2M |
BEKEKe Holdings Inc | $2.1M |
LXEOLexeo Therapeutics Inc | $2.1M |
PRQRProQR Therapeutics NV | $2.1M |
PANWPalo Alto Networks Inc | $2.0M |
SAILSailPoint Inc | $1.8M |
BDTXBlack Diamond Therapeutics Inc | $1.6M |
LXRXLexicon Pharmaceuticals Inc | $1.6M |
SAROStandardAero, Inc. | $1.5M |
BIOABIOAGE Labs Inc | $1.4M |
TRMLTourmaline Bio Inc | $1.4M |
WKWorkiva Inc | $1.3M |
BILLBILL Holdings Inc | $1.3M |
PYPLPayPal Holdings Inc | $1.3M |
GBIOGBXGeneration Bio Co | $1.2M |
SEMRSEMrush Holdings Inc | $1.2M |
PEGAPegasystems Inc | $1.1M |
MDBMongoDB Inc | $965K |
NKENike Inc | $952K |
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